Portal inflow preservation during portal diversion in small-for-size syndrome

Table 1 Operative characteristics

	Control group	S1 group	S2 group	Pvalue1	Pvalue2
Body weight (kg)	17.8 ± 3.1	18.1 ± 2.9	18.5 ± 3.9	0.85	0.87
Left trilobes (g)	351.2 ± 14.9	357.5 ± 17.2	365.5 ± 15.8	0.89	0.91
ETL (g)	443.1 ± 18.8	446.9 ± 21.5	457.0 ± 19.8	0.77	0.86
WRL (g)	391.8 ± 19.4	389.8 ± 17.4	400.8 ± 21.4	0.95	0.92
ERL(g)	51.3 ± 6.8	57.1 ± 8.5	56.2 ± 7.1	0.89	0.84
Proportion of ERL	11.8% ± 2.3%	12.8% ± 3.3%	12.2% ± 3.5%	0.87	0.83

Control group, no shunt placement; S₁ group, portal flow maintained at an average 2.0 times baseline values; S₂ group, portal flow maintained at an average 3.2 times baseline flow. Data expressed as mean ± SD. Estimated total liver volume (ETL) = (weight of left trilobes) × 100/80; WRL: Weight of resected liver; ERL: Estimated residual liver volume.

¹The difference between the control group and S₂ group;

²The difference between S₁ and S₂ groups.

Table 2 Changes in portal vein inflow and hepatic artery flow at baseline, 24 and 48 h after hepatectomy, and at euthanasia in the three groups of animals

	Control group	S1 group	S2 group	Pvalue1	Pvalue2
PVF, L/min per 100 g
BAS	59.4 ± 11.4	62.1 ± 11.4	67.4 ± 11.6	0.840	0.780
PH	451.8 ± 31.1	146.8 ± 21.1	218.8 ± 29.3	0.000	0.001
EUT	220.3 ± 41.3	69.8 ± 18.6	125.3 ± 31.6	0.000	0.000
HAF, mL/min per 100 g
BAS	19.4 ± 4.5	18.3 ± 3.4	19.9 ± 4.1	0.920	0.910
PH	6.1 ± 2.5	12.1 ± 3.5	14.9 ± 2.5	0.001	0.061
EUT	5.5 ± 2.1	11.1 ± 3.4	13.2 ± 4.2	0.000	0.052
P/A
BAS	3.1 ± 0.2	3.4 ± 0.3	3.4 ± 0.2	0.780	0.940
PH	74.0 ± 8.1	12.1 ± 2.8	14.8 ± 3.1	0.001	0.040
EUT	40.8 ± 6.6	6.3 ± 1.2	9.5 ± 1.8	0.000	0.001
PVP
BAS	6.4 ± 1.8	6.9 ± 1.3	6.0 ± 0.8	0.930	0.750
PH	13.8 ± 2.6	7.6 ± 1.6	8.7 ± 1.4	0.022	0.061
EUT	15.9 ± 2.5	8.9 ± 1.2	9.6 ± 1.5	0.001	0.042

All flow values are reported in mL/min per 100 g hepatic tissue. BAS: Baseline; EUT: Euthanasia; NS: Not significant; P/A: Portal-to-arterial flow ratio; PVF: Portal vein inflow; HAF: Hepatic artery flow.

¹The difference between the control group and S₂ group;

²The difference between the S₁ and S₂ groups.