Diagnostic value of controlled attenuation parameter for liver steatosis in patients with chronic hepatitis B

Table 1 Biochemical parameters for the 88 patients

Parameter	Value
Alanine transaminase (U/L)	61.8 ± 37.3
Aspartate aminotransferase (U/L)	73.6 ± 40.1
Albumin (g/L)	40.5 ± 22.8
Total bilirubin (μmol/L)	16.4 ± 7.8
Direct bilirubin (μmol/L)	9.4 ± 5.4
γ-glutamyl transpeptadase (U/L)	102.6 ± 65.3
Alkaline phosphatase (U/L)	99.8 ± 49.2
Body mass index (kg/m2)	24.16 ± 4.97
Triglyceride (mmol/L)	1.8 ± 1.0
Total cholesterol (mmol/L)	5.0 ± 1.7

Table 2 Relationship between controlled attenuation parameter index and hepatic steatosis stage, inflammation degree, and fibrosis degree

CAP	Hepatic steatosisdegree	Hepatic inflammation degree	Hepatic fibrosisdegree
r	0.582	-0.025	0.068
P value	< 0.05	> 0.05	> 0.05

CAP: Controlled attenuation parameter.

Table 3 Diagnostic value of controlled attenuation parameter at three decision points

Decision point	No.	Optimal cut-off point	Sensitivity	Specificity	NPV	PPV	Degree of accuracy
S1	32	219.5	0.694	0.718	71.7%	63.3%	69.5%
S2	16	230.0	0.833	0.781	89.3%	65.0%	77.3%
S3	8	283.5	1	0.969	100%	85.7%	97.4%

PPV: Positive predictive value; NPV: Negative predictive value.