Combination of symptoms, syndrome and disease: Treatment of refractory diabetic gastroparesis

Table 1 Change in nausea/vomiting subscale

Score follow-up (wk)	No.	Before treatment	After treatment	Before minus after	P value
1	33	4.18 ± 0.71	3.02 ± 1.04	1.16 ± 0.86	0.000
2	30	4.16 ± 0.73	2.32 ± 1.25	1.83 ± 1.33	0.000
4	27	4.12 ± 0.73	2.12 ± 1.26	2.00 ± 1.27	0.000
8	22	4.24 ± 0.77	1.79 ± 1.09	2.45 ± 1.06	0.000
12	12	4.25 ± 0.70	0.69 ± 0.92	3.56 ± 1.22	0.000

Table 2 Change in postprandial fullness/early satiety and bloating subscale scores

Follow-up (wk)	No.	Symptom	Before treatment	After treatment	Before minus after	P value
1	33	Fullness/early satiety	2.53 ± 1.00	2.08 ± 1.00	0.45 ± 0.60	0.000
		Bloating	1.23 ± 0.89	1.25 ± 0.80	-0.02 ± 0.59	0.882
2	30	Fullness/early satiety	2.48 ± 0.98	1.62 ± 0.95	0.86 ± 0.82	0.000
		Bloating	1.30 ± 0.89	1.03 ± 0.78	0.27 ± 0.77	0.069
4	27	Fullness/early satiety	2.64 ± 0.95	1.70 ± 1.18	2.00 ± 1.27	0.000
		Bloating	1.44 ± 0.84	1.06 ± 0.76	0.39 ± 0.66	0.005
8	22	Fullness/early satiety	2.82 ± 0.97	1.57 ± 1.09	1.25 ± 0.67	0.000
		Bloating	1.57 ± 0.81	0.91 ± 0.78	0.66 ± 0.66	0.000
12	12	Fullness/early satiety	2.81 ± 0.72	0.90 ± 0.77	1.92 ± 1.16	0.000
		Bloating	1.25 ± 0.92	0.33 ± 0.49	0.92 ± 0.76	0.002

Table 3 Change in total Gastroparesis Cardinal Symptom Index score

Follow-up (wk)	No.	Beforetreatment	After treatment	Before minus after	P value
1	33	2.66 ± 0.65	2.13 ± 0.74	0.52 ± 0.48	0.000
2	30	2.64 ± 0.64	1.66 ± 0.76	0.99 ± 0.72	0.000
4	27	2.74 ± 0.65	1.63 ± 0.87	1.11 ± 0.69	0.000
8	22	2.88 ± 0.63	1.42 ± 0.81	1.45 ± 0.5	0.000
12	12	2.77 ± 0.51	0.64 ± 0.61	2.13 ± 0.74	0.000

Table 4 Change in fasting blood glucose level

Follow-up (wk)	No.	Beforetreatment	After treatment	Before minus after	P value
1	4	11.03 ± 3.04	6.85 ± 1.51	4.18 ± 2.53	0.046
2	4	9.30 ± 3.81	9.00 ± 2.63	0.30 ± 1.98	0.781
4	13	8.84 ± 3.81	6.67 ± 1.58	2.17 ± 4.19	0.087
8	7	7.33 ± 1.77	7.30 ± 2.73	0.03 ± 3.63	0.984
12	7	7.17 ± 2.38	7.80 ± 1.88	0.63 ± 2.69	0.560