Copyright
©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. May 21, 2014; 20(19): 5897-5902
Published online May 21, 2014. doi: 10.3748/wjg.v20.i19.5897
Published online May 21, 2014. doi: 10.3748/wjg.v20.i19.5897
Table 1 Frequency of hepatitis C virus infection among high-risk groups n (%)
High-risk group | Frequency | M/F |
Addict | 550 (62.2) | 546/4 |
Thalassemia | 38 (4.3) | 17/21 |
Hemophilia | 8 (0.9) | 7/1 |
Kidney graft | 4 (0.5) | 2/2 |
Dialysis | 6 (0.7) | 5/1 |
Liver graft | 3 (0.3) | 1/2 |
Unknown | 277 (31.3) | 209/68 |
Total | 886 (100.0) | 787/99 |
Table 2 Distribution of hepatitis C virus genotypes among Iranian hepatitis C virus infected patients according to route of infection n (%)
High-risk group | Frequency | Undetectable | Gt1 | Gt2 | Gt3 | Gt4 | Gt1/2 | Gt1/3 |
Addict | 550 | 67 (12.2) | 283 (51.5) | 0 (0.0) | 192 (34.9) | 0 (0.0) | 2 (0.4) | 6 (1.1) |
Thalassemia | 38 | 15 (39.5) | 17 (44.7) | 0 (0.0) | 6 (15.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Hemophilia | 8 | 2 (25.0) | 5 (62.5) | 0 (0.0) | 1 (12.5) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Kidney graft | 4 | 1 (25.0) | 2 (50) | 0 (0.0) | 1 (25.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Dialysis | 6 | 1 (16.7) | 4 (66.7) | 0 (0.0) | 0 (0.0) | 1 (16.7) | 0 (0.0) | 0 (0.0) |
Liver graft | 3 | 1 (33.3) | 2 (66.7) | 0 (0.0) | 0 (0.) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Unknown | 277 | 64 (23.1) | 140 (50.5) | 3 (1.1) | 67 (24.2) | 3 (1.1) | 0 (0.0) | 0 (0.0) |
Total | 886 | 151 (17.0) | 453 (51.1) | 3 (0.3) | 267 (30.1) | 4 (0.5) | 2 (0.2) | 6 (0.7) |
Table 3 Comparison of illicit drug user age-groups in terms of hepatitis C virus genotypes n (%)
Undetectable | Gt1 | Gt2 | Gt3 | Gt4 | Gt1/2 | Gt1/3 | Total | |
< 20 | 0 (0.0) | 1 (33.3) | 0 (0.0) | 2 (66.66) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 3 (0.57) |
21-30 | 14 (11.02) | 59 (46.45) | 0 (0.0) | 53 (41.73) | 0 (0.0) | 0 (0.0) | 1 (0.78) | 127 (24.47) |
31-40 | 23 (10.95) | 113 (53.80) | 0 (0.0) | 69 (32.85) | 0 (0.0) | 2 (0.95) | 3 (1.42) | 210 (40.46) |
41-50 | 18 (16.36) | 58 (52.72) | 0 (0.0) | 33 (30) | 0 (0.0) | 0 (0.0) | 1 (0.9) | 110 (21.19) |
51-60 | 6 (11.53) | 25 (48.07) | 0 (0.0) | 20 (38.46) | 0 (0.0) | 0 (0.0) | 1 (1.92) | 52 (10.01) |
> 60 | 1 (5.88) | 10 (58.82) | 0 (0.0) | 6 (35.29) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 17 (3.27) |
Total | 62 (11.9) | 266 (51.25) | 0 (0.0) | 183 (35.26) | 0 (0.0) | 2 (0.38) | 6 (1.15) | 519 (100.0) |
Table 4 Comparison of hepatitis C virus genotypes in the addict and non-addict high-risk groups
Genotype | Non-addict | Addict |
Gt1 | 50.7% | 51.5% |
Gt2 | 1.0% | 0.0% |
Gt3 | 22.0% | 34.9% |
Gt4 | 1.3% | 0.0% |
Gt1/2 | 0.0% | 0.4% |
G1/3 | 0.0% | 1.1% |
Unknown | 25.0% | 12.2% |
Table 5 Important risk factors in Iranian illicit drug users n (%)
HCV infection | +Imprisonment and tattoo | +Imprisonment | + No other risk factor | Total |
Injection Drug Users | 70 | 235 | 134 | 439 (80) |
Non-Injection Drug Users | 63 | 23 | 25 | 111 (20) |
Total | 133 (24) | 265 (48) | 159 (28) | 550 (100) |
- Citation: Jamalidoust M, Namayandeh M, Asaei S, Aliabadi N, Ziyaeyan M. Determining hepatitis C virus genotype distribution among high-risk groups in Iran using real-time PCR. World J Gastroenterol 2014; 20(19): 5897-5902
- URL: https://www.wjgnet.com/1007-9327/full/v20/i19/5897.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i19.5897