Expression of Bmi-1 and PAI-1 in esophageal squamous cell carcinoma

Table 1 B-cell-specific moloney leukemia virus insert site 1 protein expression in esophageal cancer and normal esophageal tissues

Pathological characteristic	Total cases	Bmi-1			χ2	Pvalue
		Positive	Negative	Positive rate (%)
Cancerous tissue	80	63	17	78.7	37.77	0.01
Normal tissue	20	1	19	5.0

Bmi-1: B-cell-specific moloney leukemia virus insert site 1.

Table 2 Plasminogen activator inhibitor-1 protein expression in esophageal cancer and normal esophageal tissues

Pathological characteristic	Total cases	PAI-1			χ2	Pvalue
		Positive	Negative	Positive rate (%)
Cancerous tissue	80	61	19	75.0	28.69	0.01
Normal tissue	20	2	18	10.0

PAI-1: Plasminogen activator inhibitor-1.

Table 3 Correlation between B-cell-specific moloney leukemia virus insert site 1 expression and clinicopathological data

Characteristic	Total cases	Positive cases	Positive rate (%)	χ2	Pvalue
Differentiation degree
Moderate to high	46	38	82.6	0.963	0.411
Poor	34	25	73.5
Lymphatic metastasis
Yes	27	17	63.0	6.07	0.024
No	53	46	86.6
Sex
Male	57	47	73.5	1.627	0.234
Female	23	16	82.6
Age (yr)
< 60	34	25	87.5	0.963	0.414
≥ 60	46	38	70.0
Nationality
Han	40	35	78.8	3.66	0.099
Kazakh	40	28	78.7
Tumor size (cm)
≤ 3	33	26	92.3	0	0.613
> 3	47	37	72.2
Depth of infiltration
Muscular layer	26	24	92.3	4.231	0.0451
Tunica externa	54	39	72.2
Pathological type
Ulcerative	37	27	73.0	0.885	0.829
Fungating	11	10	90.9
Medullary	26	21	80.7
Constrictive	6	5	83.3

Table 4 Correlation between plasminogen activator inhibitor-1 expression and clinicopathological data

Characteristic	Total cases	Positive cases	Positive rate (%)	χ2	P value
Differentiation degree
Moderate to high	46	39	84.8	4.351	0.061
Poor	34	22	64.7
Lymphatic metastasis
Yes	27	16	59.3	6.497	0.024
No	53	45	84.9
Sex
Male	57	44	77.2	0.097	0.777
Female	23	17	73.9
Age (yr)
< 60	34	29	85.3	2.671	0.119
≥ 60	46	32	69.6
Nationality
Han	40	30	75.0	0.069	1.000
Kazakh	40	31	77.5
Tumor size (cm)
≤ 3	33	25	75.8	0.008	1.000
> 3	47	36	76.6
Depth of infiltration
Muscular layer	26	14	53.8	10.676	0.022
Tunica externa	54	47	87.0
Pathological type
Ulcerative	37	27	73.0	0.580	0.901
Fungating	11	9	81.8
Medullary	26	20	76.9
Constrictive	6	5	76.0