HBsAg levels in HBeAg-positive chronic hepatitis B patients with different immune conditions

doi:10.3748/wjg.v20.i15.4407

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 21, 2014; 20(15): 4407-4413
Published online Apr 21, 2014. doi: 10.3748/wjg.v20.i15.4407

Table 1 Baseline characteristics of three groups of hepatitis B e antigen -positive chronic hepatitis B patients

Variables	IT group (n = 72)	IC-Mild group (n = 72)	ACLF group (n = 36)	Kruskal-Wallis test P value
Age (yr)	25 (22-29)	30 (24-37)	34 (28-41)	< 0.001
Gender (male/female)	44/28	55/17	32/4	0.006
HBV DNA (log₁₀ IU/mL)	8.39 (8.15-8.65)	7.58 (7.11-8.79)	6.33 (4.67-7.17)	< 0.001
HBsAg (log₁₀ IU/mL)	4.86 (4.54-4.97)	3.97 (3.67-4.43)	3.57 (2.74-4.03)	< 0.001
ALT (IU/mL)	25 (19-32)	220 (118-282)	468 (244-779)	< 0.001
TB (μmol/L)	11 (9-15)	16 (10-29)	314 (248-443)	< 0.001
INR	1.01 (0.81-1.07)	1.08 (0.85-1.17)	2.24 (1.74-2.71)	< 0.001
PLT (10⁹/L)	210 (187-273)	172 (152-298)	124 (103-167)	< 0.001

Data are expressed as the median (interquartile range) or as a ratio. CHB: Chronic hepatitis B; IT: Immune-tolerant patients; IC-Mild: Patients with a mild immune response in the immune clearance phase; ACLF: Patients with a dramatic immune response in the immune clearance phase and exhibiting acute on chronic liver failure; ALT: Alanine aminotransferase; WBC: White blood cell; PLT: Platelet; TB: Total bilirubin; INR: International normalized ratio.

Citation: Zhang YM, Yang YD, Jia HY, Zeng LY, Yu W, Zhou N, Li LJ. HBsAg levels in HBeAg-positive chronic hepatitis B patients with different immune conditions. World J Gastroenterol 2014; 20(15): 4407-4413
URL: https://www.wjgnet.com/1007-9327/full/v20/i15/4407.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i15.4407