Interleukin 28B polymorphisms as predictor of response in hepatitis C virus genotype 2 and 3 infected patients

Table 1 Prevalence and impact of interleukin 28B rs12979860 in studies combining genotype 2 and genotype 3

Study	No. of patients	Prevalence	Treatment	RVR in	SVR in
		of IL-28B CC	duration	IL-28B CC	IL-28B CC
		genotype	(wk)	genotype	genotype
Mangia et al[10]	268	41%	12-24	59%	79%
Sarrazin et al[11]	2671	43%	24-48	51%	47%
Lindh et al[13]	341	44%	12-24	67%	70%
Bitetto et al[19]	101	37%	24	na	78%

¹Follow-up information not available in all patients. RVR: Rapid virological response; SVR: Sustained virological response; IL: Interleukin.

Table 2 Prevalence and impact of interleukin 28B rs12979860 in studies analyzing genotype 3 separately

Study	No. of patients	Prevalence of	Treatment	RVR in	SVR in
		IL-28B CC	duration	IL-28B CC	IL-28B CC
		Genotype	(wk)	genotype	genotype
Scherzer et al[12]	71	38%	2	78%	76%
Moghaddam et al[14]	281	46%	14-24	84%	77%
Fattovich et al[20]	55	51%	24	86%	87%
Mangia et al[21]	470	41%	12-24	80%	84%

RVR: Rapid virological response; SVR: Sustained virological response; IL: Interleukin.