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©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 7, 2013; 19(33): 5421-5429
Published online Sep 7, 2013. doi: 10.3748/wjg.v19.i33.5421
Published online Sep 7, 2013. doi: 10.3748/wjg.v19.i33.5421
Table 1 Cumulative effectiveness of pneumatic dilations for treatment of achalasia by using low compliance “Rigiflex” dilators
No. | Type of dilator (size, cm) | Improvement excellent/good | Mean follow-up (yr) | Complication perforation | Ref. |
125 | 3.0-4.0 | 50% | 12.00% | 0.01% | [27] |
54 | BMD | 36%-40% | 13.80% | 0.02% | [13] |
262 | 3.0-3.5 | 60% | 4.50% | 1.00% | [14] |
66 | 3.0-4.0 | 79% | 4.60% | 5.00% | [15] |
39 | 3.0-4.0 | 58.3%-78.0% | 9.30% | 5.40% | [24] |
50 | 3.0-4.0 | 67%-83% | 2.70% | 0.00% | [25] |
106 | 3.0-4.0 | 28%-62% | 3.20% | 2.80% | [28] |
209 | 3.0-4.0 | 72% | 5.80% | 0.00% | [23] |
55 | 3.0-3.5 | 74.50% | 2.30% | 0.00% | [22] |
43 | 3.0-3.5 | 54%-78% | 2.40% | 2.30% | [17] |
56 | 3.5 | 89.3%-92.9% | 0.50% | 0.00% | [21] |
32 | 3.0 | 69%-91% | 4.50% | 3.30% | [20] |
1097 | 3.0-4.0 | 28.0%-92.9% | 0.5%-15.0% | 1.0%-2.0% | Total |
Table 2 Cumulative effectiveness of surgical myotomy for achalasia
No. | Type of surgery | Improvement excellent/good | Mean follow-up (yr) | Complication acid reflux | Ref. |
52 | LHM-Dor operation | 92% | 4.3 | 11% | [51] |
53 | LHM-Dor operation | 92% | 3.0 | 9% | [61] |
75 | LHM-partial fundoplication | 84% | 5.6 | 15% | [48] |
71 | LHM-Dor | 85% | 6.0 | 12.70% | [52] |
248 | LHM+/-Dor | 88% | 3.4 | 3% | [55] |
211 | LHM-Dor | 89% | 5.3 | 34% | [56] |
161 | LHM-Dor | 97.20% | 4.6 | 15.70% | [47] |
200 | LHM-Dor | 85% | 3.5 | 28% | [57] |
46 | LHM-Toupet or Dor | 80% | 6.4 | 9% | [46] |
505 | LHM+/- fundoplication | 95% | 2.6 | 16% | [51] |
155 | LHM-Dor | 77% | 5.0 | 27% | [54] |
137 | LHM-Dor | 94.80% | 5.4 | 10.90% | [59] |
1860 | - | 77%-97.2% | 2.6-10.9 | 3%-34% | Total |
Table 3 Summary of the cumulative efficacies and complications of current treatment options of achalasia
PD | Surgical myotomy | BTI | POEM | |
No. of studies | 12 | 12 | 9 | 11 |
No. of patients | 1097 | 1860 | 315 | 210 |
Excellent/good symptom response (range) | 28%-92.9% | 77%-97.2% | At 1 mo: 79% (64%-93%) At 1 yr: 41% (10%-55%) | 82%-100% |
Follow up (yr) | 0.5-15 | 2.6-10.9 | 18 (6-30) | 0.1-1 |
Major complications (range) | 1%-2% Perforation | 3%-34% Acid reflux | - | 0.03% Acid reflux |
- Citation: Chuah SK, Chiu CH, Tai WC, Lee JH, Lu HI, Changchien CS, Tseng PH, Wu KL. Current status in the treatment options for esophageal achalasia. World J Gastroenterol 2013; 19(33): 5421-5429
- URL: https://www.wjgnet.com/1007-9327/full/v19/i33/5421.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i33.5421