Human platelets inhibit liver fibrosis in severe combined immunodeficiency mice

Table 1 Liver regeneration indices and spleen/body weight ratios, serum asparatate aminotransferase, alanine aminotransferase, total bilirubin, albumin, and total cholesterol concentrations

	Liver/body weight ratio	PCNA labeling index (/HPF)	Mitotic index (/HPF)	Spleen/body weight ratio	AST (U/mL)	ALT (U/mL)	T-bil (mg/mL)	Alb (g/mL)	T-CHO (g/mL)
PBS	6.2% ± 0.5%	2.1 ± 0.9	0.6 ± 0.3	0.23% ± 0.04%	50 ± 21	122 ± 56	1.0 ± 0.2	3.0 ± 1.0	77.8 ± 5.4
hPLT	6.7% ± 0.5%	2.4 ± 0.9	0.6 ± 0.5	0.24% ± 0.05%	50 ± 15	104 ± 64	0.8 ± 0.2	3.0 ± 1.5	82.7 ± 4.4a

n = 8 per group.

^aP < 0.05 for the human platelet transfusions (hPLT) group vs the phosphate-buffered saline (PBS) group. PCNA: Proliferating cell antigen; HPF: High-power field; AST: Asparatate aminotransferase; ALT: Alanine aminotransferase; T-bil: Total bilirubin; Alb: Albumin; T-CHO: Total cholesterol.