Epidemiology of perforated peptic ulcer: Age- and gender-adjusted analysis of incidence and mortality

Table 1 Patient characteristics according to ulcer localisation n (%)

	Duodenal ulcer	Gastric ulcer	Total	P value
	n = 60	n = 112	n = 172
Age
< 60 yr	18 (30)	37 (33)	55 (32)	0.68
≥ 60 yr	42 (70)	75 (67)	117 (68)
Gender
Female	27 (45)	62 (55)	89 (52)	0.20
Male	33 (55)	50 (45)	83 (48)
ASA status				0.99
1	0	0	0
2	2 (3)	3 (3)	5 (3)
3	34 (57)	63 (56)	97 (56)
4	20 (33)	39 (35)	59 (34)
5	4 (7)	7 (6)	11 (6)
Social status				0.32
Married	37 (62)	58 (52)	95 (55)
Divorced	3 (5)	8 (7)	11 (6)
Widowed	9 (15)	28 (25)	37 (22)
Single	6 (10)	7 (6)	13 (8)
Unknown	5 (8)	11 (10)	16 (9)
Smokers1	26 (54)	60 (69)	86 (64)	0.09
NSAID-use	26 (43)	50 (45)	76 (44)	0.87
Steroid-use	5 (8)	11 (10)	16 (9)	0.73
Comorbidity	45 (75)	97 (87)	142 (82)	0.06
Cardiovascular disease	27 (45)	50 (45)	77 (45)	0.89
Pulmonary disease	8 (13)	19 (17)	27 (16)	0.53
Autoimmune disease	13 (22)	18 (16)	31 (18)	0.36
Malignancy (past or current)	6 (10)	23 (21)	29 (17)	0.08
Past ulcer history	8 (13)	18 (16)	26 (15)	0.36
30-d mortality	14 (23)	14 (13)	28 (16)	0.07

P values are for trends across groups. Percentages may not add up due to rounding.

¹Data on smoking was missing in 37 (22%) of patients. Per centages are of patients with reported data (n = 135). ASA: American Society of Anesthesiology; NSAIDs: Non-steroidal anti-inflammatory drugs.