Unusual histopathological findings in appendectomy specimens from patients with suspected acute appendicitis

Table 1 Clinicopathologic characteristics of the 1621 patients who underwent appendectomy n (%)

Patient characteristics	Results
Patients	1621
Sex
Male	912 (56.3)
Female	709 (43.7)
Age in years, mean (range)
Overall	36.7 ± 17.4 (16-94)
Male	36.2 ± 17.5 (16-89)
Female	37.3 ± 17.3 (16-94)
Distribution of patients according to age range (yr)
16-20	275
21-30	526
31-40	290
41-50	165
51-60	146
61-70	134
≥ 71	85
Histopathologic findings
Suppurative appendicitis	789 (48.7)
Appendix vermiformis	370 (22.8)
Gangrenous appendicitis-perforated	243 (15.0)
Unusual histopathologic findings	134 (8.3)
Phlegmonous appendicitis	53
Gangrenous appendicitis	32
Age distribution of the 370 patients with negative appendectomy (yr)
16-20	67
21-30	111
31-40	61
41-50	35
51-60	32
61-70	43
≥ 71	21

Table 2 Detailed characteristics of 134 patients with unusual histopathological findings

Patient characteristic	Results
Patients	134
Sex, n (%)
Male	60 (44.8)
Female	74 (55.2)
Age in years, mean ± SD (range)
Overall	48.4 ± 19.5 (16-94)
Male	50.9 ± 19.3 (16-87)
Female	46.4 ± 19.5 (16-94)
Histopathologic findings, n
Fibrous obliteration	62
Enterobius vermicularis	31
Eosinophilic infiltration	10
Mucinous cystadenoma	8
Carcinoid tumor	6
Granulomatous inflammation	5
Adenocarcinoma	3
Mucinous adenocarcinoma	1
Mucocele	3
Adenomatous polyp	1
Taenia saginata	1
Ascaris lumbricoides	1
Non-Hodgkin’s lymphoma (B cell)	1
Appendicular diverticulitis	1
Age distribution of 134 patients with unusual findings (yr)
16-20	8
21-30	30
31-40	15
41-50	16
51-60	22
61-70	22
≥ 71	21

Table 3 Detailed characteristics of the 11 patients with appendicular malignancy

No.	Age (yr)	Sex	Primary tumor type	Tumor size (mm)	Pleomorphism	Mitosis (HPF)	Necrosis	Parietal spread	Surgical approach
1	55	M	B-NHL	CD20(+), CD79a(+)					Appendectomy
2	64	F	Adenoca	40				Muscularis propria	Appendectomy-right hemicolectomy
3	67	M	Adenoca	15					Appendectomy-right hemicolectomy
4	74	F	Adenoca	50				Serosa	Appendectomy-right hemicolectomy
5	51	M	Adenoca	50				Serosa	Appendectomy-right hemicolectomy
6	41	F	Carcinoid	25	Minimal	1/10	No	Mesoappendix	Appendectomy-right hemicolectomy
7	28	F	Carcinoid	5	Minimal	1/10	No	Submucosa	Appendectomy
8	28	F	Carcinoid	8	Minimal	0/10	No	Mesoappendix	Appendectomy
9	60	F	Carcinoid	10	Moderate	2/10	No	Mesoappendix	Appendectomy
10	21	M	Carcinoid	12	Moderate	2/10	No	Mesoappendix	Appendectomy
11	52	F	Carcinoid	13	Moderate	1/10	No	Muscularis propria	Appendectomy

HPF: High power field; M: Male; F: Female; B-NHL: B cell non-Hodgkins lymphoma.