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World J Gastroenterol. Jun 28, 2013; 19(24): 3861-3865
Published online Jun 28, 2013. doi: 10.3748/wjg.v19.i24.3861
Published online Jun 28, 2013. doi: 10.3748/wjg.v19.i24.3861
HCC group | LC group | t orχ2value | P value | |
No. of patients | 81 | 183 | ||
Age (yr; mean ± SD) | 53.86 ± 11.05 | 52.66 ± 11.42 | -0.797 | 0.426 |
Sex (male) | 65 | 129 | 2.742 | 0.098 |
HBeAg positive | 18 | 37 | 0.137 | 0.712 |
Serum HBV DNA loads (log10 copies/mL) | 5.43 ± 1.16 | 5.25 ± 1.28 | -1.077 | 0.283 |
Spontaneous YMDD mutation | 13 | 7 | 11.983 | 0.001 |
Genotype C virus | 33 | 33 | 15.441 | 0.000 |
Genotype B virus | 47 | 146 | 13.518 | 0.000 |
Co-infected by genotype B and C viruses | 1 | 4 | - | - |
Related factors | B | SE | Wald | P value | Exp (B) | 95%CI |
Sex (male) | 0.749 | 0.353 | 4.500 | 0.034 | 2.114 | 1.059-4.224 |
HBV genotype C strain | 0.904 | 0.335 | 7.257 | 0.007 | 2.469 | 1.279-4.764 |
Spontaneous YMDD mutation in genotype C strain | 2.051 | 0.826 | 6.161 | 0.013 | 7.775 | 1.540-39.264 |
- Citation: Yang JH, Zhang H, Chen XB, Chen G, Wang X. Relationship between hepatocellular carcinoma and hepatitis B virus genotype with spontaneous YMDD mutations. World J Gastroenterol 2013; 19(24): 3861-3865
- URL: https://www.wjgnet.com/1007-9327/full/v19/i24/3861.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i24.3861