Is proliferative colonic disease presentation changing?

Table 1 Characteristics of the 768 patients with colorectal cancer n (%)

	Period A (1989-1993)	Period B (2003-2007)	P value
	352 patients	416 patients
Male	202 (57.4)	253 (60.8)	0.335
Female	150 (42.6)	163 (39.2)
Age (yr)
< 50	49 (13.9)	27 (6.5)	< 0.0001
50-59	70 (19.9)	55 (13.2)
60-69	121 (34.4)	95 (22.8)
70-79	90 (25.6)	180 (43.3)
≥ 80	22 (6.2)	59 (14.2)

Table 2 Characteristics of the 978 patients with polyps n (%)

	Period A (1989-1993)273 patients	Period B (2003-2007)705 patients	P value
Male	178 (65.2)	418 (59.3)	0.0892
Female	95 (34.8)	287 (40.7)
Age (yr)
< 50	50 (19.2)	91 (12.9)	< 0.0015
50-59	44 (16.9)	154 (21.9)
60-69	103 (39.5)	226 (32.1)
70-79	57 (21.8)	185 (26.3)
≥ 80	7 (2.7)	48 (6.8)
Total No. of polyps	428	1265
No. of polyps, mean ± SD	1.6 ± 1	1.8 ± 1.3	0.0102
No. of polyps, median	1	1
Range	1-6	1-14
Dimensions
< 5 mm	114 (26.6)	530 (41.9)	< 0.00005
5-9 mm	228 (53.3)	454 (35.9)
10-19 mm	44 (10.3)	191 (15.1)
20-29 mm	23 (5.4)	52 (4.1)
30-39 mm	9 (2.1)	25 (2)
40+ mm	10 (2.3)	13 (1)
Histopathological pattern
Hyperplastic	91 (33.6)	438 (38.7)	< 0.00005
Mild/moderate dispalsia1	151 (55.7)	597 (52.7)
Severe dysplasia2	27 (10)	87 (7.7)
Others3	2 (0.7)	10 (0.9)

¹Tubular, mixed or villous adenoma with mild or low grade dysplasia;

²Tubular, mixed or villous adenoma with severe dysplasia or cancer in situ or serrated adenoma;

³Lymphatic lump, hamartoma, leiomyoma, anal human papilloma virus.