New approach to anal cancer: Individualized therapy based on sentinel lymph node biopsy

Table 1 Technical aspects and results of the published case series

Ref.	Year	T stage	Groin clinical	Tot N cases	Inguinal detection rate (%)	Double tracer	N positive (%)	Complication	Bilateral detection	Surgical retrieval rate
Keshtgar et al[56]	2000	NA	Negative	1	1/1	Yes	1/1	NA	0/1	1/1
Perera et al[58]	2002	T1-T2	1/12	12	8/12 (66)	Yes	2/18 (11)	NA	0/8	8/8
Péley et al[57]	2002	NA	1/8	8	8/8 (100)	Yes	2/8 (25)	No complication	5/8	8/8
Rabbit et al[69]	2002	NA	Negative	4	3/4 (75)	Yes	0/3 (0)	NA	2/3	3/3
Bobin et al[62]	2003	NA	Negative	33	33/33 (100)	Yes	7/33 (21.2)	NA	NA	33/33
Ulmer et al[60]	2004	T2-T4	Negative	17	13/17 (76)	Yes	5/12 (41.6)	Lymphatic fistula (1 pt)	4/13	12/12
Gretschel et al[54]	2008	T1-T4	Negative	40	20/40 (50)	Yes	6/20 (30)	Wound infection (2 pts), lymphatic fistula (1 pt), hematoma (1 pt)	NA	20/20
Mistrangelo et al[64]	2009	T1-T4	NA	35	35/35 (100)	No	7/35 (20)	Lymphatic fistula (18 pts), lower limb lymphedema (1 pt)	22/35	34/35
Damin et al[55]	2010	T1-T3	Negative	15	15/15 (100)	Yes	4/15 (26.6)	Lymphatic fistula (1 pt)	13/15	15/15
de Jong et al[70]	2010	T1-T3	4/21	21	21/21 (100)	Yes	7/21 (33)	NA	14/21	21/21
De Nardi et al[43]	2011	T1-T3	Negative	11	9/11 (81)	Yes	3/9 (33)	Lymphatic fistula (1 pt)	2/11	9/9

NA: Not applicable.