Impact of body mass index and gender on quality of life in patients with gastroesophageal reflux disease

Table 1 Basic characteristics of the three groups of patients with gastroesophageal reflux disease

Variable	Normal weight (n = 102)		Overweight (n = 56)		Obese (n = 15)		P value
	n (%)	mean ± SD	n (%)	mean ± SD	n (%)	mean ± SD
Age (yr)		44.32 ± 15.14		50.77 ± 15.88		41.47 ± 12.24	0.4232
Gender							0.0011
Male	33 (32.4)		41 (73.2)		11 (73.3)
Female	69 (67.6)		15 (26.8)		4 (26.7)
Symptom duration (mo)		2.17 ± 3.16		2.64 ± 3.69		3.15 ± 4.30	0.4062
NERD	62 (60.8)		20 (35.7)		4 (26.7)		0.0021
EE	40 (39.2)		36 (64.3)		11 (73.3)
Hiatal hernia	17 (16.7)		19 (33.9)		9 (60.0)		0.0011
ECJ ulcer	7 (6.9)		5 (8.9)		2 (13.3)		0.6661

¹Pearson’s Chi-square test;

²Analysis of variance. ECJ: Esophagocardiac junction; EE: Erosive esophagitis; NERD: Non-erosive reflux disease.

Table 2 Basic characteristic of the three groups of male and female patients with gastroesophageal reflux disease

Variable	Normal weight (n = 102)		Overweight (n = 56)		Obesity (n = 15)		P value
	n (%)	mean ± SD	n (%)	mean ± SD	n (%)	mean ± SD
Male	33 (38.8)		41 (48.3)		11(12.9)
Mean age (yr)		51.88 ± 16.93		52.54 ± 16.96		39.64 ± 11.09	0.1052
NERD	20 (60.6)		10 (24.4)		4 (36.4)		0.0071
EE	13 (39.4)		31 (75.6)		7 (63.6)
Hiatal hernia	10 (30.3)		14 (34.1)		7 (63.6)		0.1261
ECJ ulcer	5 (15.2)		5 (12.2)		2 (18.2)		0.8591
Female	69 (78.4)		15 (17.1)		4 (4.5)
Age (yr)		40.71 ± 12.84		45.93 ± 11.59		46.50 ± 15.59	0.2482
NERD	42 (60.9)		10 (66.7)		0		0.0451
EE	27 (39.1)		5 (33.3)		4 (100)
Hiatal hernia	7 (10.1)		5 (33.3)		2 (50.0)		0.0141
ECJ ulcer	2 (2.9)		0		0		0.7541

¹Pearson’s χ² test;

²Analysis of variance. ECJ: Esophagocardiac junction; EE: Erosive esophagitis; NERD: Non-erosive reflux disease.