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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 21, 2012; 18(35): 4892-4897
Published online Sep 21, 2012. doi: 10.3748/wjg.v18.i35.4892
Published online Sep 21, 2012. doi: 10.3748/wjg.v18.i35.4892
Table 1 Characteristics of patients
IL28B polymorphism | n (%) | SVR (%) | Gender (M/F) | Age (yr) | BMI(kg/m2) |
CC | 13 (20) | 77 | |||
CT | 34 (53) | 38 | |||
TT | 17 (27) | 6 | |||
All | 64 | 39 | 27/37 | 44 ± 12 | 27 ± 5 |
Table 2 Odds ratios of sustained virological response, depending on type of polymorphism of IL28B, inflammation activity, fibrosis, fatty liver, baseline hepatitis C virus viral load, the level of platelets and insulin resistance
Features affecting SVR | P value | OR | 95% CI |
CC vs TT | < 0.001 | 25 | 3.5-177.5 |
Platelets CT | 0.002 | 12.8 | 1.8-42.6 |
Staging | 0.008 | 5.9 | 1.5-23.8 |
CC vs CT | 0.018 | 5.4 | 1.2 -23.3 |
Fatty liver | 0.014 | 4.8 | 1.2-13.6 |
Platelets | 0.005 | 4.7 | 1.3-17.3 |
Grading | 0.026 | 3.9 | 1.1-13.4 |
Insulin resistance | 0.029 | 3.9 | 1.1-13.8 |
HCV viremia | 0.038 | 3 | 1-8.8 |
- Citation: Cieśla A, Bociąga-Jasik M, Sobczyk-Krupiarz I, Głowacki MK, Owczarek D, Cibor D, Sanak M, Mach T. IL28B polymorphism as a predictor of antiviral response in chronic hepatitis C. World J Gastroenterol 2012; 18(35): 4892-4897
- URL: https://www.wjgnet.com/1007-9327/full/v18/i35/4892.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i35.4892