Brief Article
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 28, 2012; 18(32): 4371-4378
Published online Aug 28, 2012. doi: 10.3748/wjg.v18.i32.4371
Table 1 Demographic and clinical characteristics of gastro-esophageal reflux disease patients and healthy volunteers n (%)
Demographic and clinical parametersGERD patientsHVsP value
Patients4048
Female/male20/2027/21NS
Mean age, yr (range)48 (18-76)44 (22-77)NS
Mean BMI, kg/m2 (range)26 (20-32)23 (16-34)< 0.05
NERD/ERD25 (63)/15 (38)NA
Patients with hiatal hernia22 (55)4 (10)< 0.01
Patients responding to PPI therapy34 (85)NA
Table 2 Impedance-pH features in gastro-esophageal reflux disease patients and healthy volunteers
Impedance-pH featuresGERD patientsHVsP value
% pH < 4 upright6.9 (5.5-12; 28)1 (0.2-1.9; 5)< 0.0001
% pH < 4 recumbent3.5 (1.2-7; 18)0 (0-0.1; 2.1)< 0.0001
% pH < 4 total5.5 (4.3-9; 22)0.7 (0.2-1.4; 4.2)< 0.0001
GER total65 (54-108; 177)32 (18-43; 54)< 0.0001
GER acid53 (34-72; 95)17 (8-31; 45)< 0.0001
GER nonacid20 (15-37; 116)18 (14-26; 45) 0.0615
Prox. extension31 (20-48; 86)9 (4-17; 30)< 0.0001