Natural orifice transluminal endoscopic surgery vs laparoscopic ovariectomy: Complications and inflammatory response

doi:10.3748/wjg.v18.i27.3558

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 21, 2012; 18(27): 3558-3564
Published online Jul 21, 2012. doi: 10.3748/wjg.v18.i27.3558

Table 1 Necropsy findings 4 wk after the procedure n (%)

	Laparoscopy	Notes
Adhesions	3 (30)	4 (40)	NS
Abscess	0	1 (10)¹	NS
Peritonitis	0	0	NS
Pigs without any complication	7 (70)	5 (50)	NS

¹Small intramural abscess (8 mm) at the healed gastrotomy site. NS: Not significant.

Table 2 Parameters of systemic inflammatory response

	NOTES (n = 10)				Laparoscopy (n = 10)
	Before	POD 2	POD 7	PODs 28-30	Before	POD 2	POD 7	PODs 28-30
CRP (mg/L)	14.5 (12-17)	52.6 (47-73)^a^c	51.8 (31-88)^a^c	22.1 (14-38)	16.1 (11-35)	37.1 (23-70)^c	51.4 (33-55)^c	20 (16-31)
WBC (× 10⁹/L)	14.9 (14-17)	19.6 (15-21)	19.7 (17-23)^a	15.3 (15-20)	18.3 (14-23)	23.5 (19-24)^c	20 (18-26)^c	15.4 (14-18)
IL-6 (ng/L)	108 (105-118)	115 (110-121)	110 (100-123)	104 (97-129)	92 (79-117)	103.5 (90-146)	98.6 (85-178)	111 (67-130)
Platelets (× 10⁹/L)	414 (400-465)	314 (261-351)^a^c	366 (336-442)	381 (325-479)	424 (313-540)	273 (253-412)^a^e	433 (381-641)	389 (382-498)

Data is median with interquartile range.

^aP < 0.05 vs before the procedure;

^cP < 0.05 vs POD 28-30;

^eP < 0.05 vs post-operative day (POD) 7 and PODs 28-30, no significant differences between the groups [natural orifice transluminal endoscopic surgery (NOTES) vs laparoscopy]. CRP: C-reactive protein; WBC: White blood count; IL-6: Interleukin 6.

Table 3 Diversion ratios from preoperative values

	POD 2		POD 7		POD 28
	NOTES	Laparoscopy	NOTES	Laparoscopy	NOTES	Laparoscopy
CRP (%)	288 (207-357)	64 (4-172)^a	154 (70-436)	172 (60-273)	31.6 (3-193)	25 [(-57)-76]
WBC (%)	16 (0.3-43)	21 [(-6)-66]	34 (13-42)	33 [(-8)-60]	8 [(-0.3)-26]	-15 [(-23)-10]
IL-6 (%)	3.7 (1.6-9)	6 (3-15)	-1.6 [(-8)-0.9]	6.6 (0.9-19)	-9.8 [(-21)-(-1.6)]	-6.7 [(-21)-44]
Platelets (%)	-23.5 [(-24)-(-13)]	-17.6 [(-35)-(-10)]	1.5 [(-13)-19)]	21 (9-30)	2 [(-11)-7]	3 [(-2)-12]

Diversion rate (%): (Postoperative value-preoperative value/preoperative value) × 100. Data is median with interquartile range.

^aP = 0.01 vs natural orifice transluminal endoscopic surgery (NOTES), no other significant differences between NOTES and laparoscopy groups. POD: Post-operative day; CRP: C-reactive protein; WBC: White blood count; IL-6: Interleukin 6.

Citation: Martínek J, Ryska O, Filípková T, Doležel R, Juhas S, Motlík J, Holubová M, Nosek V, Rotnáglová B, Zavoral M, Ryska M. Natural orifice transluminal endoscopic surgery vs laparoscopic ovariectomy: Complications and inflammatory response. World J Gastroenterol 2012; 18(27): 3558-3564
URL: https://www.wjgnet.com/1007-9327/full/v18/i27/3558.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i27.3558