Helpfulness of the combination of acetic acid and FICE in the detection of Barrett's epithelium and Barrett's associated neoplasias

Table 1 Clinical characteristics of patients undergoing combined acetic acid and Fujinon intelligent chromoendoscopy endoscopy

	Normal mucosa	SIM or LGD	HGD or carcinoma	All patients
Number of patients (%)	5 (25)	8 (40)	7 (35)	20
Age (yr) (mean ± SD)	56.4 ± 21.7	65 ± 10.5	71 ± 13.8	65 ± 15
Sex (men/women)	5/0	7/1	7/0	19/1
Concomitant therapy PPI (%)	60	100	100	90
Median Barrett’s oesophagus	1 (0-1)	2.3 (2-3.3)	3.5 (2.5-3.6)	2 ± 1.3
Length (cm) ± IQR

SIM: Specialized intestinal metaplasia; LGD: Low-grade dysplasia; HGD: High-grade dysplasia; PPI: Proton-pump inhibitor; IQR: Interquartile range.

Table 2 Correlation of the predominant mucosal and vascular patterns with histological results during high resolution white light endoscopy or after 2% acetic acid pulverisation and Fujinon intelligent chromoendoscopy 0, 4 and 7

	High resolution white light			Acetic acid pulverisation and FICE
	Normal histology	SIM or LGD	HGD or carcinoma	Normal histology	SIM or LGD	HGD or carcinoma
Number of patients (%)	5	8	7	5	8	7
Regular or not visualized mucosal pattern1 (%)	100	100	86	100	100	0
Irregular mucosal pattern (%)	0	0	14	0	0	100
Regular or not visualized vascular pattern1 (%)	100	100	100	100	100	14
Abnormal blood vessels (%)	0	0	14	0	0	86
Raised lesion (%)	0	0	14	0	0	71
Pigmented lesion (%)	0	0	0	0	37.5	0
Bleeding lesion (%)	0	0	14	0	0	57
Ulcerous lesion (%)	0	14	14	0	14	14

FICE: Fujinon intelligent chromoendoscopy; SIM: Specialized intestinal metaplasia; HGD: High-grade dysplasia; LGD: Indicate Low grade dysplasia.

¹Endoscopists were not able to exactly classify the mucosal pattern according to Sharma’s classification of mucosal pattern due to lack of visibility, but they judged that the mucosa was regular.