Comparison of PPIs and H2-receptor antagonists plus prokinetics for dysmotility-like dyspepsia

Table 1 Baseline demographic characteristics and total symptom scores for study completers

	H2RA + Prok(n = 57)	PPI(n = 57)	P value
Age (mean ± SD, yr)	51.5 ± 14.8	52.9 ± 13.8	0.6120
Sex (male/female)	17/40	12/45	0.3899
Helicobacter pylori infection (%)	43.8	43.8	> 0.9999
Symptom scores
Upper abdominal bloating	1.6 ± 1.2	1.8 ± 1.3	0.6160
Postprandial fullness	2.1 ± 1.2	2.0 ± 1.2	0.7747
Early satiation	1.7 ± 1.3	1.3 ± 1.2	0.1934
Belching	1.7 ± 1.4	1.6 ± 1.4	0.7211
Vomiting/nausea	1.5 ± 1.3	1.4 ± 1.3	0.8361
Total symptom score (dysmotility-like dyspepsia symptoms)	8.6 ± 3.9	8.2 ± 4.7	0.5330

PPI: Proton pump inhibitor. H₂RA: H₂-receptor antagonist; Prok: Plus prokinetic.

Table 2 Multiple logistic regression analysis of treatment response

Variable	Estimated OR	95% CI	P value
Age (yr)	0.999	0.962-1.036	0.9493
Sex: male	0.853	0.312-2.332	0.7563
Helicobacter pylori infection	0.521	0.191-1.419	0.2019
Treatment: PPI	9.055	3.231-25.376	< 0.0001
Dysmotility-like symptom score	1.062	0.940-1.200	0.3368

OR: Odds ratio; PPI: Proton pump inhibitor.