Influence of proton pump inhibitor treatment on Helicobacter pylori stool antigen test

Table 1 Results of urea breath test and stool antigen tests before proton pump inhibitor administration

	Urea breath test
	Positive	Negative	Total
Stool antigen test
Positive	20	2	22
Negative	1	5	6
Total	21	7	28

Sensitivity 95.2% (20/21), specificity 71.4% (5/7), agreement 89.3% (25/28).

Table 2 Results of urea breath test and stool antigen tests after proton pump inhibitor administration

	Urea breath test
	Positive	Negative	Total
Stool antigen test
Positive	16	1	17
Negative	2	9	11
Total	18	10	28

Sensitivity 88.9% (16/18), specificity 90.9% (9/10), agreement 89.3% (25/28).

Table 3 Differences in positivity rates from before to after proton pump inhibitor treatment

	BeforePPI treatment	AfterPPI treatment	P value
Urea breath test	75.0% (21/28)	64.3% (18/28)	0.55
Stool antigen test	78.6% (22/28)	60.7% (17/28)	0.15

PPI: Proton pump inhibitor.