Five methods for detection of Helicobacter pylori in the Turkish population

Table 1 Statistical analysis according to standard test

Method	Sensitivity	Specificity	PPV	NPV	OR	RR
Culture	0.6118	0.9149	0.9286	0.4342	16.94	2.14
HpSA	0.7222	0.6667	0.8125	0.4545	5.20	1.79
Biopsy PCR	0.8824	0.5106	0.7653	0.2941	7.83	2.60
Stool PCR	0.2118	0.7872	0.6429	0.6442	0.99	1.00
FISH	0.9294	0.9574	0.9753	0.1176	296.25	8.29

PPV: Positive predictive value; NPV: Negative predictive value; OR: Odds ratio; RR: Relative risk; HpSA: Helicobacter pylori stool antigen; PCR: Polymerase chain reaction; FISH: Fluorescence in situ hybridization.

Table 2 Test results compared to standard test

Method	False positive	False negative	r	P value
Culture	4	33	0.5101	< 0.001
HpSA	12	20	0.2761	< 0.002
Biopsy PCR	23	10	0.4301	< 0.001
Stool PCR	10	67	0.001	> 0.05
FISH	2	6	0.8721	< 0.001

¹Correlation is significant at the 0.01 level. HpSA: Helicobacter pylori stool antigen; PCR: Polymerase chain reaction; FISH: Fluorescence in situ hybridization.