Topic Highlight
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. May 28, 2011; 17(20): 2500-2506
Published online May 28, 2011. doi: 10.3748/wjg.v17.i20.2500
Table 1 Common mechanisms of liver/hepatocyte damage
EffectHIVHCVAlcoholHAART
Increase ROS
Increase proinflammatory cytokines
Oxidative stress
Lipid peroxidation
Mitochondrial damage
Steatosis
Glutathione depletion
Proteasome dysfunction