Faria GR, Almeida AB, Moreira H, Pinto-de-Sousa J, Correia-da-Silva P, Pimenta AP. Acute diverticulitis in younger patients: Any rationale for a different approach? World J Gastroenterol 2011; 17(2): 207-212 [PMID: 21245993 DOI: 10.3748/wjg.v17.i2.207]
Corresponding Author of This Article
Gil R Faria, MD, MSc, Department of General Surgery, Hospital de São João, Al. Prof. Hernâni Monteiro, HSJ, 4200-319 Porto, Portugal. gilfaria@netcabo.pt
Article-Type of This Article
Brief Article
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World J Gastroenterol. Jan 14, 2011; 17(2): 207-212 Published online Jan 14, 2011. doi: 10.3748/wjg.v17.i2.207
Table 1 Clinical and laboratory features of the 2 groups of patients according to age n (%)
Group A ( ≤50 yr)
Group B (> 50 yr)
P
Signs and symptoms
Abdominal pain
30 (96.7)
117 (92.8)
NS
Fever
9 (29.0)
30 (23.8)
NS
Acute abdomen
10 (32.3)
30 (23.8)
NS
Vomiting
5 (16.1)
26 (20.6)
NS
Constipation
3 (9.7)
23 (18.2)
NS
Diarrhea
2 (6.4)
13 (10.3)
NS
Laboratory
Leucocytosis (> 11 × 109)
24 (82.7)
67 (55.8)
0.01
Mean WBC count (× 109)
15.0
13.1
0.01
Mean CRP (mg/dL)
151.5
133.5
0.005
Table 2 Severity of disease (Hinchey classification) and surgical treatment of the 2 groups according to age n (%)
Group A ( ≤50 yr)
Group B (> 50 yr)
P
Disease severity
0.01
Uncomplicated
27 (87.1)
80 (63.5)
Complicated
4 (12.9)
46 (36.5)
Complication grading
0.04
Grade I/II
3 (9.7)
30 (23.8)
Grade III/IV
1 (3.2)
16 (12.7)
Surgical treatment
Emergency surgery
1 (3.2)
18 (14.3)
0.03
Elective surgery
4 (16.1)
5 (4.0)
0.07
Table 3 Recurrence and severity of recurrent disease in the 2 groups according to age n (%)
Group A ( ≤50 yr)
Group B (> 50 yr)
P
Disease recurrence
0.03
Non recurrent
23 (74.2)
112 (88.9)
Recurrent
8 (25.8)
14 (11.1)
Severity of recurrence
0.10
Non complicated
6 (75)
10 (71)
Complicated (Grade I)
2 (25)
4 (29)
Table 4 Multivariate analysis of recurrence factors in patients with diverticulitis
Factor
Binary regression logistics
Exp (B)
P
Male gender
1.13
0.827
Age ≤ 50 yr
0.26
0.024
White blood cell count (× 109)
0.99
0.830
Severity index
1.08
0.798
Citation: Faria GR, Almeida AB, Moreira H, Pinto-de-Sousa J, Correia-da-Silva P, Pimenta AP. Acute diverticulitis in younger patients: Any rationale for a different approach? World J Gastroenterol 2011; 17(2): 207-212