Review
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. May 21, 2011; 17(19): 2372-2378
Published online May 21, 2011. doi: 10.3748/wjg.v17.i19.2372
Table 1 Histological classification of tumor-like primary hepatic space-occupying lesions
Hepatocellular lesions
Focal nodular hyperplasia[2]
Nodular regenerative hyperplasia[2]
Partial nodular transformation[3]
Adenomatoid hyperplasia (dysplastic nodules)[2]
Compensatory lobar or segmental hyperplasia[4]
Focal fatty change[2]
Accessory lobe[5]
Bile duct lesions
Biliary microhamartoma (Von Meyenburg complex)[2]
Cyst and polycystic liver[6]
Ciliated foregut cyst[7]
Epidermoid cyst[8]
Endometrial cyst[9]
Intrahepatic peribiliary gland cyst[2]
Mesothelial cyst[10]
Cystic echinococcosis[11]
Biloma[12]
Miscellaneous lesions
Mesenchymal hamartoma[2]
Inflammatory pseudotumor[2]
Pseudolymphoma[13]
Solitary necrotic nodule[14]
Peliosis hepatis[15]
Hereditary hemmorrhagic telangiectasia[16]
Sarcoidosis[17]
Nodular extramedullary hematopoiesis[18]
Abscess[19]
Tuberculoma[20]
Botryomycosis[21]
Malacoplakia[22]
Ectopic tissue[23] and adrenal rest tumor[24]
Pseudolipoma[2]
Granulomas[25]
Table 2 Histological classification of benign primary hepatic space-occupying lesions
Hepatocellular tumors
Hepatocellular adenoma[2] and hepatic adenomatosis[33]
Intrahepatic bile duct tumors
Bile duct cystadenoma[2]
Intraductal papillary neoplasm[34] and intraductal papillomatosis[2]
Bile duct adenoma[2]
Biliary adenofibroma[35]
Vascular and lymphoid tumors
Cavernous hemangioma[2]
Perivascular epithelioid cell tumor[36]
Hemangioblastoma[37]
Infantile hemangioendothelioma[2]
Lymphangioma and lymphangiomatosis[2]
Muscle, fibrous and adipose tumors
Angiomyolipoma[2]
Leiomyoma[38]
Solitary fibrous tumor[2]
Lipoma[39]
Myelolipoma[40]
Neuronal and neuroendocrine tumors
Neurilemmoma[41]
Plexiform neurofibroma[42] and plexiform neurofibromatosis[43]
Paraganglioma[44]
Pheochromocytoma[45]
Gastrinoma[46]
Vascoactive intestinal peptide tumor[47]
Somatostatinoma[48]
Miscellaneous tumors
Teratoma[49]
Mesothelioma[50]
Endometrioma[51]
Chondroma[52]
Myxoma[53]
Langerhan’s cell histiocytosis[54]
Desmoplastic nested spindle cell tumor[55]
Spongiotic pericytoma[56]
Table 3 Histological classification of malignant primary hepatic space-occupying lesions
Hepatocellular tumors
Hepatocellular carcinoma[2]
Hepatoblastoma[2]
Combined hepatocellular and cholangiocarcinoma[2]
Intrahepatic bile duct tumors
Intrahepatic cholangiocarcinoma[2]
Cholangiolocellular carcinoma[62]
Bile duct cystadenocarcinoma[2]
Biliary rhabdomyosarcoma[63]
Solid-pseudopapilary tumor[64]
Vascular, lymphoid and haemopoietic tumors
Angiosarcoma[2]
Malignant angiomyolipoma[60]/malignant perivascular epithelioid
cell tumor[61]
Malignant hemangiopericytoma[65]
Epithelioid hemangioendothelioma[2]
Kaposi’s sarcoma[2]
Lymphoma[2]
Follicular dendritic cell sarcoma/tumor[66]
Extramedullary plasmacytoma[67]
Muscle, fibrous and adipose tumors
Leiomyosarcoma[68]
Rhabdomyosarcoma[69]
Fibrosarcoma[70]
Malignant fibrous histocytoma[71]
Liposarcoma[72]
Neuronal and neuroendocrine tumors
Carcinoid tumor[73]
Malignant neurilemmoma[74]
Miscellaneous tumors
Undifferentiated embryonal sarcoma[75]
Undifferentiated carcinoma[76]
Carcinosarcoma[2]
Lymphoepithelioma-like carcinoma[77]
Squamous cell carcinoma[78]
Germ cell tumor[79]
Chorioepithelioma[80]
Yolk sac tumor[81]
Immature teratoma[82]
Malignant rhabdoid tumor[83]
Malignant mesothelioma[84]
Synovial sarcoma[85]
Epithelial-myoepithelial carcinoma[86]
Gastrointestinal stromal tumor[87]
Osteosarcoma[88]
Osteoclast-like giant cell tumor[89]
Desmoplastic small round cell tumor[90]
Nested stromal-epithelial tumor[91]/ossifying stromal epithelial tumor[92]