Harimoto N, Shirabe K, Abe T, Yukaya T, Tsujita E, Gion T, Kajiyama K, Nagaie T. Prospective randomized controlled trial investigating the type of sutures used during hepatectomy. World J Gastroenterol 2011; 17(18): 2338-2342 [PMID: 21633600 DOI: 10.3748/wjg.v17.i18.2338]
Corresponding Author of This Article
Norifumi Harimoto, MD, PhD, Department of Surgery, Iizuka Hospital, 3-83 Yoshio-machi Iizuka-city, Fukuoka 820-8505, Japan. nharimotoh1@aih-net.com
Article-Type of This Article
Brief Article
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World J Gastroenterol. May 14, 2011; 17(18): 2338-2342 Published online May 14, 2011. doi: 10.3748/wjg.v17.i18.2338
Table 1 Comparison of clinicopathological data of the groups
Variables
Vicryl group
Silk group
P-value
(n = 62)
(n = 63)
Age
68 ± 10
67 ± 12
0.684
Male/female
37/25
41/22
0.720
Body mass index
22.6 ± 3.0
23.7 ± 12
0.159
Diabetes mellitus (%)
19.4
33.0
0.104
HBV (%)
17.7
20.6
0.560
HCV (%)
50.0
39.7
0.666
Albumin (g/dL)
3.6 ± 0.5
3.6 ± 0.5
0.694
Total bilirubin (mg/dL)
0.7 ± 0.4
0.7 ± 0.4
0.813
AST (IU/L)
46 ± 31
43 ± 27
0.592
Platelet count (x 104/μL)
21.0 ± 11.0
19.7 ± 10.1
0.460
ICGR15 (%)
15.4 ± 9.0
16.4 ± 11.9
0.589
Child-Pugh A/B
58/4
59/4
0.999
HCC/non-HCC
46/16
47/16
0.826
Liver cirrhosis (ch/lf/lc)
15/20/27
15/22/26
0.948
Anatomical/nonanatomical
20/42
20/43
0.618
Operation time (min)
273 ± 88
276 ± 105
0.876
Blood loss (g)
698 ± 894
763 ± 1329
0.749
Transfusion (%)
12.9
17.4
0.620
Bile leakage (%)
3.2
6.3
0.680
Total SSI (%)
11.3
15.8
0.603
Incisional SSI (%)
8.0
9.5
0.999
Organ/space SSI (%)
3.2
6.3
0.680
Remote infection (%)
3.2
1.6
0.546
Hospital stay (d)
16 ± 15
16 ± 14
0.880
Table 2 Comparison of clinicopathological data of the groups
Variables
SSI(+)
SSI(-)
P-value
(n = 17)
(n = 108)
Age
68 ± 10
67 ± 11
0.667
Male/female
13 /4
65/43
0.287
Body mass index
24.3 ± 5.2
23.0 ± 3.9
0.208
Diabetes mellitus (%)
35.3
25.0
0.384
HBV (%)
23.5
18.5
0.703
HCV (%)
64.7
41.7
0.560
Albumin (g/dL)
3.6 ± 0.4
3.6 ± 0.5
0.977
Total bilirubin (mg/dL)
0.7 ± 0.3
0.7 ± 0.4
0.938
AST (IU/L)
56 ± 22
43 ± 29
0.070
Platelet count (x 104/μL)
20.7 ± 7.3
20.4 ± 11.0
0.904
ICGR15 (%)
19.9 ± 8.3
15.3 ± 10.7
0.101
Child-Pugh A/B
17/0
100/8
0.597
HCC/non-HCC
15/2
78/30
0.638
Liver cirrhosis (ch/lf/lc)
2/7/8
28/35/45
0.435
Anatomical/nonanatomical
8/9
32/76
0.228
Operation time
> 265 min (%)
76.5
44.4
< 0.050
Blood loss
> 1000 g (%)
41.2
18.5
< 0.050
Transfusion (%)
11.8
15.7
0.999
Bile leakage (%)
35.3
0
< 0.010
Vicryl/silk
7/10
55/53
0.603
Hospital stay (d)
29 ± 23
15 ± 12
< 0.010
Table 3 Multivariate logistic stepwise regression analysis for predictive factors of surgical site infection
Adjusted odds ratios (95% CI)
P value
Blood loss
> 1000 g
7.598 (1.396-41.364)
< 0.010
Table 4 Comparison of the period for recovery in patients with surgical site infection
Vicryl
28 ± 11 d
Silk
54 ± 30 d
Citation: Harimoto N, Shirabe K, Abe T, Yukaya T, Tsujita E, Gion T, Kajiyama K, Nagaie T. Prospective randomized controlled trial investigating the type of sutures used during hepatectomy. World J Gastroenterol 2011; 17(18): 2338-2342