Apoptotic bone marrow CD34+ cells in cirrhotic patients

Table 1 Characteristics of patients in cirrhosis and control groups

Parameters	Control	Child-Pugh A	Child-Pugh B	Child-Pugh C	P value (cirrhosis vs control)
Demographic data
Number	15	12	11	8
Male/female	9/6	6/6	6/5	5/3
Age	42 (32-53)	39 (35-50)	46 (32-60)	48 (29-60)	NS
Lab tests
WBC (× 109)	7.05 ± 2.21	4.34 ± 2.01	2.93 ± 0.50	3.62 ± 1.78	< 0.01
RBC (× 1012)	3.53 ± 0.60	3.67 ± 0.61	3.93 ± 0.75	3.34 ± 0.57	NS
PLT (× 109)	210 ± 105	141 ± 114	58 ± 42	54 ± 27	< 0.01
ALT(IU/L)	16 ± 14	55 ± 49	87 ± 48	61 ± 31	< 0.01
AST(IU/L)	20 ± 11	50 ± 33	73 ± 24	106 ± 63	< 0.01
Albumin (g/L)	43 ± 5	40 ± 6	35 ± 3	30 ± 6	< 0.01
TBIL (μmol/L)	10.3 ± 3.5	15.8 ± 7.6	40.7 ± 23.0	78.4 ± 57.8	< 0.01
γ-GT(IU/L)	15 ± 12	64 ± 63	143 ± 171	100 ± 108	< 0.01

TBIL: Total bilirubin; NS: No significance.

Table 2 Correlation between early, late and total CD34+ cells and laboratory parameters

Parameters	Early apoptotic cells		Late apoptotic cells		Total CD34+ cells
	r	P	r	P	r	P
Age	-0.124	0.625	0.225	0.385	0.048	0.839
RBC	0.024	0.924	-0.181	0.487	-0.107	0.653
WBC	-0.152	0.548	0.244	0.345	0.322	0.167
PLT	-0.216	0.389	0.195	0.452	0.218	0.355
TBIL	-0.186	0.490	0.717	0.003b	0.314	0.205
ALT	-0.015	0.957	0.256	0.358	0.206	0.412
AST	-0.043	0.874	0.663	0.007b	0.146	0.564
γ-GT	-0.117	0.667	0.136	0.630	0.471	0.048a
Albumin	-0.283	0.270	-0.033	0.905	0.465	0.045a

^aP < 0.05,

^bP < 0.01 vs early apoptotic cells.