Brief Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Apr 21, 2011; 17(15): 1996-2002
Published online Apr 21, 2011. doi: 10.3748/wjg.v17.i15.1996
Table 1 Microscopic colitis cases identified by IHC using CD3
No. of cases1P value
Cases marked as normal, chronic inflammation or melanosis coli241
IELs > 2020< 0.001
Known case of LC10.158
Missed LC5< 0.001
Collagenous colitis20.078
Microscopic colitis (Total No. of cases)8< 0.001
Table 2 Clinicopathological features and follow-up data in patients with > 20 intra-epithelial lymphocytes
AgeSexIEL countPresenting symptomOriginal biopsy diagnosisFollow-up period for 2 yr
32F22Chronic diarrheaNormalLymphocytic colitis12
32F27Chronic diarrheaNormalLymphocytic colitis2
55F27ConstipationNormalResolve
65M26Abdominal painNormalMyelodysplastic syndrome
22F31ConstipationNormalLost to follow up
35M38Chronic diarrheaNormalLymphocytic colitis1
42F30ConstipationNormalLost to follow up
59F28Abdominal painNormalResolve
59F40Chronic diarrheaNormalMultiple liver lesions
56M31Chronic diarrheaNormalUlcerative colitis
79F20Abdominal painMelanosis coliDiverticulitis
19F28Abdominal painNormalBehcet’s disease
24F24Chronic diarrheaNormalLymphocytic colitis2
51M48Chronic diarrheaNormalMetastatic renal cell carcinoma
56F30Chronic diarrheaNormalLymphocytic colitis2
34F30Abdominal painNormalResolved
33F30Chronic diarrheaLymphocytic colitisLymphocytic colitis3
71M20Loss of weightNormalDiverticulitis
59F25Abdominal painNormalResolve
35F35Abdominal painMelanosis coliPancreatitis
Table 3 Clinicopathological features and follow-up data on patients with chronic diarrhea and 10-19 Intra-epithelial lymphocytes
AgeSexIEL countOriginal diagnosisComorbid diseaseFollow-up period for 2 yr
DiagnosisDiarrhea
54F10Chronic inflammationDiabetic hypertensionLactose intolerantPersistent
70F12Melanosis coliDiabeticAutonomic neuropathyPersistent
22M13Chronic inflammationLost to FULost to FU
64M15Melanosis coliDiabetic, asthmaticAutonomic neuropathyPersistent
59F16Melanosis coliSchistosomiasis contactIrritable bowel syndromePersistent
64F18NormalDiabetic, asthmatic, previous sigmoidectomy for benign strictureHypothyroidPersistent