Factors associated with irritable bowel syndrome symptoms in hemodialysis patients

Table 1 Patients’ demographic and clinical data expressed as (mean ± SD) n (%)

Group	IBS symptoms		All	P value
	(+)	(-)
n	27	169	196
Gender (M/F)	13/14	105/64	118 / 78	0.168
Age (yr)	68.1 ± 11.5	63.2 ± 13.4	63.9 ± 13.2	0.073
Dialysis duration (min)	40.1 ± 36.9	38.6 ± 45.8	38.8 ± 44.6	0.874
BMI (kg//m2)	25.0 ± 3.7	24.9 ± 4.9	24.9 ± 4.7	0.897
Residual diuresis (mL/24 h)	301 ± 559	401 ± 592	388 ± 42	0.411
Kt/V	1.26 ± 0.31	1.21 ± 0.27	1.22 ± 0.28	0.355
Hepatitis C or B infection (n)	7 (25.9%)	31 (18.3%)	38 (19.4%)	0.430
Hemoglobin (g/dL)	11.4 ± 1.4	10.7 ± 1.5	10.8 ± 1.5	0.026a
Albumin (g/dL)	3.72 ± 0.40	3.71 ± 0.44	3.71 ± 0.44	0.857
Smoking (n)	7 (25.9%)	23 (13.6%)	30 (15,3%)	0.144

IBS: Irritable bowel syndrome; BMI: Body mass index.

^aP < 0.05.

Table 2 Multiple logistic regression analysis to identify independent predictors of irritable bowel syndrome symptoms in hemodialysis patients

Variable	b coefficient (SE)	P value	OR (95% CI)
Potassium level pre-HD	-0.325 ± 0.437	0.457	0.723 (0.307-1.703)
Potassium level post-HD	-1.356 ± 0.633	0.032a	0.258 (0.075-0.891)
Paracetamol use	1.150 ± 0.488	0.018a	3.159 (1.214-8.220)
Cognitive function	-0.023 ± 0.011	0.042a	0.977 (0.956-0.999)
Hemoglobin	0.327 ± 0.168	0.052	1.387 (0.998-1.928)
Age	0.026 ± 0.021	0.213	1.027 (0.985-1.070)

HD: Hemodialysis; OR : Odds ratio.

^aP < 0.05.