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World J Gastroenterol. Apr 7, 2011; 17(13): 1746-1752
Published online Apr 7, 2011. doi: 10.3748/wjg.v17.i13.1746
Published online Apr 7, 2011. doi: 10.3748/wjg.v17.i13.1746
Table 1 Effects of carbachol on hemodynamic parameters in oral resuscitation of burn shock (mean ± SD)
Post-burn (h) | MAP (mmHg) | CO (L/min) | PV (mL/kg) | ||||||
NR | OR | OR/CAR | NR | OR | OR/CAR | NR | OR | OR/CAR | |
0 | 135 ± 9.3 | 131 ± 18.7 | 128 ± 12.6 | 2.46 ± 0.13 | 2.43 ± 0.17 | 2.39 ± 0.19 | 49.6 ± 5.6 | 46.8 ± 4.2 | 48.3 ± 4.0 |
2 | 100 ± 7.2a | 94 ± 15.3a | 89 ± 10.0a | 1.28 ± 0.11a | 1.34 ± 0.1a | 1.30 ± 0.11a | 38.2 ± 3.8a | 40.3 ± 3.0a | 41.3 ± 3.1a |
4 | 108 ± 8.3a | 136 ± 18.9b | 130 ± 15.1b | 1.12 ± 0.10a | 1.54 ± 0.11ab | 1.48 ± 0.12ab | 32.8 ± 2.3a | 39.0 ± 3.8a | 40.8 ± 3.9a |
8 | 120 ± 14.3 | 125 ± 15.9 | 127 ± 14.3 | 1.20 ± 0.17a | 1.65 ± 0.12ab | 1.86 ± 0.14abc | 30.9 ± 3.4a | 36.2 ± 3.4ab | 42.2 ± 3.4abc |
24 | 124 ± 8.9 | 126 ± 8.8 | 129 ± 8.9 | 1.07 ± 0.17a | 1.94 ± 0.18ab | 2.16 ± 0.15abc | 30.6 ± 4.4a | 40.4 ± 3.0ab | 45.8 ± 3.6bc |
48 | 129 ± 8.7 | 135 ± 20.8 | 123 ± 15.8 | 1.88 ± 0.15a | 2.39 ± 0.23b | 2.49 ± 0.16b | 34.5 ± 2.4a | 43.0 ± 3.8b | 45.6 ± 3.6b |
72 | 115 ± 13.7a | 137 ± 11.0b | 135 ± 13.1b | 2.10 ± 0.13a | 2.34 ± 0.12b | 2.41 ± 0.20b | 35.8 ± 2.9a | 43.8 ± 3.4b | 45.8 ± 4.0b |
120 | 112 ± 11.4a | 134 ± 14.6b | 131 ± 14.2b | 2.15 ± 0.15a | 2.39 ± 0.15b | 2.41 ± 0.20b | 37.6 ± 3.5a | 44.7 ± 3.2b | 46.9 ± 3.4b |
Table 2 Effect of carbachol on gastrointestinal perfusion in oral resuscitation of burn shock (mean ± SD)
Post-burn (h) | PgCO2 (mmHg) | IMBF (BPU) | ||||
NR | OR | OR/CAR | NR | OR | OR/CAR | |
0 | 32.2 ± 3.7 | 33.2 ± 6.1 | 33.8 ± 6.8 | 203.8 ± 17.6 | 198.3 ± 11.9 | 207.3 ± 13.9 |
2 | 73.1 ± 7.7a | 60.8 ± 8.2ab | 57.4 ± 8.0ab | 74.2 ± 10.8a | 101.2 ± 12.2ab | 112.6 ± 10.2ab |
4 | 83.1 ± 6.5a | 74.0 ± 6.5ab | 70.0 ± 6.2ab | 71.5 ± 15.3a | 108.8 ± 12.2ab | 138.8 ± 14.1abc |
8 | 86.4 ± 8.6a | 69.2 ± 6.8ab | 68.5 ± 5.8ab | 77.8 ± 10.0a | 114.7 ± 12.0ab | 134.7 ± 13.9abc |
24 | 82.5 ± 7.6a | 65.8 ± 5.8ab | 56.4 ± 4.7a, b, | 79.2 ± 17.3a | 127.7 ± 11.9ab | 157.7 ± 17.7abc |
48 | 61.5 ± 8.2a | 56.0 ± 8.4a | 57.0 ± 6.4a | 146.8 ± 13.8a | 159.3 ± 19.1a | 179.3 ± 19.1ab |
72 | 56.8 ± 6.6a | 39.4 ± 8.9b | 35.4 ± 5.6b | 168.5 ± 9.7a | 180.7 ± 18.5 | 198.7 ± 16.5b |
120 | 45.8 ± 6.2a | 31.2 ± 5.0b | 34.2 ± 4.0b | 178.8 ± 16.5a | 203.5 ± 23.2b | 200.5 ± 18.2b |
- Citation: Hu S, Che JW, Tian YJ, Sheng ZY. Carbachol promotes gastrointestinal function during oral resuscitation of burn shock. World J Gastroenterol 2011; 17(13): 1746-1752
- URL: https://www.wjgnet.com/1007-9327/full/v17/i13/1746.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i13.1746