Primary mixed germ cell tumor of the liver with sarcomatous components

doi:10.3748/wjg.v16.i5.652

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 16, Issue 5

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (6169)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-3) series, Tables (1-1) series.

Item

Count

PDF

372

HTML

5167

Figures (1-3)

415

Tables (1-1)

215

Sum=6169

Feb 7, 2010 (publication date) through Dec 20, 2024

Times Cited of This Article

Times Cited (13)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

World J Gastroenterol. Feb 7, 2010; 16(5): 652-656
Published online Feb 7, 2010. doi: 10.3748/wjg.v16.i5.652

Table 1 Immunohistochemical and FISH profiles of tumor that is considered in the differential diagnosis of GCT of the liver

Markers	Yolk sac tumor component	Immature glandular structure	Primitive mesenchymal component	Rhabdomyoblastic component	Chondroid and osteoblastic components	Neuroblastoma component
Antigen
AFP	+++	+¹	-	-	+	-
AE1/AE3	+++	+++	-	-	-	-
Hep par 1	-	+	-	-	-	-
CK7	-	+	-	-	-	-
CK18	+	+++	-	-	-	-
CK19	+++	+++	-	-	-	-
CK20	-	+	-	-	-	-
EMA	-	+	-	-	-	-
α-1-antitrypsin	+	+	-	-	-	-
α-1-chymotrypsin	-	+	-	-	-	-
pCEA	-	++	-	-	-	-
mCEA	-	++	-	-	-	-
Vimentin	-	-	+++	+++	++	+++
Desmin	-	-	-	+++	-	-
Myoglobin	-	-	-	+++	-	-
SMA	-	-	+¹	-	-	-
CD30	-	-	-	-	-	-
HCG	-	-	-	-	-	-
GFAP	+	-	-	-	-	++
NSE	-	-	++	-	-	+++
S-100	-	-	-	-	++	++
Synaptophysin	-	-	-	-	-	++
PLAP	-	-	-	-	-	-
CD56	-	-	+	-	-	++
HMB45	-	-	-	-	-	+¹
CD117	-	-	++	-	-	-
CD34	-	-	+¹	-	-	-
Ki67	+++	+++	+	++	-	+++
P53	+++	+++	-	++	-	++
CD45	-	-	-	-	-	-
FISH	+	+	-	+	-	-

¹Focal. +: Positive; ++: Strongly positive; -: Negative; FISH: Fluorescence in situ hybridization; GCT: Germ cell tumor; AFP: α-fetoprotein; EMA: Epithelial membrane antigen; CEA: Carcinoembryonic antigen; SMA: Smooth muscle actin; HCG: Human chorionic gonadotropin; GFAP: Glial fibrillary acid protein; NSE: Neuron-specific enolase; PLAP: Placental alkaline phosphatase.

Citation: Xu AM, Gong SJ, Song WH, Li XW, Pan CH, Zhu JJ, Wu MC. Primary mixed germ cell tumor of the liver with sarcomatous components. World J Gastroenterol 2010; 16(5): 652-656
URL: https://www.wjgnet.com/1007-9327/full/v16/i5/652.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i5.652