Antimicrobial susceptibility of Helicobacter pylori strains isolated from patients in Shiraz, Southern Iran

Table 1 Rates of antibiotic resistance in Helicobacter pylori isolates in relation to patient gender

Sex No.	No. of isolates (% of resistance)
	MTZ	AMX	CLA	TET
Male (n = 50)	17 (34)	9 (18)	1 (2)	1 (2)
Female (n = 71)	36 (50)	15 (21)	5 (7)	3 (4)
Total (n = 121)	53 (43)	24 (19)	6 (5)	4 (3)

MTZ: Metronidazole; AMX: Amoxicillin; CLA: Clarithromycin; TET: Tetracycline.

Table 2 Antibiotic resistance patterns of the Helicobacter pylori strains

Antibiotic resistance patterns	n	Male	Female
MTZ	44	15	29
AMX	14	7	7
CLA	1	0	1
TET	1	1	0
MTZ-AMX	3	1	2
MTZ-TET	1	0	1
AMX-TET	1	0	1
AMX-CLA	1	0	1
MTZ-AMX-TET	1	0	1
MTZ-AMX-CLA	4	1	3
Sensitive	50	25	25
Total	121	50	71

MTZ: Metronidazole; AMX: Amoxicillin; CLA: Clarithromycin; TET: Tetracycline.

Table 3 Range of minimum inhibitory concentrations for antibiotics tested against Helicobacter pylori strains in relation to patient gender

Sex	Range of MICs for antibiotics (mg/L)
	MTZ	AMX	CLA	TET
Male	0.064 to > 256	< 0.016 to > 256	< 0.016 to 64	0.016 to 8
Female	0.047 to > 256	< 0.016 to > 256	< 0.016 to > 256	0.016 to 8

MIC: Minimum inhibitory concentration; MTZ: Metronidazole; AMX: Amoxicillin; CLA: Clarithromycin; TET: Tetracycline.