Relationship between RGS5 expression and differentiation and angiogenesis of gastric carcinoma

Table 1 Relationship between clinical parameters of patients and expression of regulator of G-protein signaling 5 in gastric carcinoma

Variables	n	+	++	+++	++++	Spearman correlation	P
Differentiation						0.345	0.000
Low	24	16	4	4	0
Moderate	30	4	8	12	6
High	22	6	8	0	8
Gender						-0.219	0.059
Male	46	12	14	8	12
Female	30	14	6	8	2
Lymph node metastasis						0.082	0.343
Positive	22	8	8	2	4
Negative	54	18	12	14	10
Tumor size (cm)						-0.053	0.766
≤ 4	58	20	14	12	12
> 4	18	6	6	4	2
Age (yr)						0.122	0.197
≤ 55	36	16	6	8	6
> 55	40	10	14	8	8
Clinical stages						-0.192	0.184
I	42	12	8	12	10
II	12	6	4	2	0
III	22	8	8	2	4

Table 2 Relationship between microvascular density and clinical parameters of patients and expression of regulator of G-protein signaling 5 in gastric carcinoma

Variables	n	MVD (mean ± SD)	P
Gender
Male	46	11.08 ± 7.87	0.221
Female	30	16.07 ± 13.99
Lymph node metastasis
Positive	22	19.17 ± 12.03	0.014
Negative	54	10.29 ± 9.04
Tumor size (cm)
≤ 4	58	13.59 ± 12.06	0.548
> 4	18	11.27 ± 5.87
Age (yr)
≤ 55	36	11.61 ± 10.23	0.481
> 55	40	14.05 ± 11.17
Expression of RGS5
High	30	9.15 ± 7.16	0.023
Low	46	16.75 ± 12.37

MVD: Microvascular density; RGS5: Regulator of G-protein signaling 5.