Comparative study of therapeutic effects of PPI and H2RA on ulcers during continuous aspirin therapy

Table 1 Background of patients n (%)

	PPI group (n = 26)	H2RA group (n = 26)	P value
Median age (yr)	67.2 ± 8.7	71.1 ± 6.9	NS
Male	19 (73.1)	19 (73.1)	NS
Ischemic heart disease	15 (57.7)	13 (50.0)	NS
Smoking	11 (42.3)	8 (30.8)	NS
Helicobacter pylori (+)	13 (50.0)	12 (46.2)	NS
Ulcer size > 5 mm	13 (50.0)	12 (46.2)	NS
Location of mucosal defect
Stomach	24	23	NS
Duodenal	2	3
Aspirin
Buffered	10	10	NS
Enteric-coated	16	16

PPI: Proton pump inhibitors; H2RA: Histamine 2 receptor antagonists; NS: Not significant.