Endoscopic mucosal resection of colorectal polyps in typical UK hospitals

Table 1 Patient demographics n (%)

	No. of patients (n = 199)
Age (yr)1	68.0 ± 11.4
Sex
M	119 (59.8)
F	80 (40.2)
Polyp location
Cecum	49 (20.5)
Ascending colon	30 (12.6)
Transverse colon	26 (10.9)
Descending colon	34 (14.2)
Sigmoid colon	43 (18.0)
Rectum	57 (23.8)
Total	239
Polyp size (mm)1	68.0 ± 11.4
Range (mm)	10-80

¹Values are mean ± SD. Values are number of patients with percentages in parentheses unless indicated otherwise.

Table 2 Characteristics of polyps according to histopathology n (%)

	Non-adenomas	Adenomas	Carcinoma-in-situ
Age (yr)1	61.3 ± 12.9	69.2 ± 9.9	76.2 ± 11.2
Sex
M	15	117	9
F	23	64	4
Polyp size (mm)1	13.9 ± 5.2	20.8 ± 13.1	22.7 ± 14.9
Polyp location
Cecum	13 (34.2)	31 (17.1)	2 (15.4)
Ascending colon	5 (13.2)	24 (13.3)	0
Transverse colon	9 (23.7)	15 (8.3)	1 (7.7)
Descending colon	4 (10.5)	29 (16.0)	0
Sigmoid colon	6 (15.8)	33 (18.2)	3 (2.3)
Rectum	1 (2.6)	49 (27.1)	7 (5.4)
Total	38	181	13
Resection method
En bloc	33 (86.8)	129 (71.3)	9 (69.2)
Piecemeal	5 (13.2)	50 (27.6)	4 (30.8)
Not recorded	0	2 (1.1)	0
Complete resection
Yes	36 (94.7)	154 (85.1)	10 (76.9)
No	2 (5.3)	26 (14.4)	3 (23.1)
Not recorded	0	1 (0.5)	0
Recurrence2
No		75 (48.8)	1 (10.0)
Yes		30 (19.4)	3 (30.0)
No follow up		49 (31.8)	6 (60.0)

¹Values are mean ± SD;

²Only completely resected lesions were assessed for recurrence. Values are number of patients with percentages in parentheses unless indicated otherwise.

Table 3 Hazard ratio for risk of recurrence associated with clinical variables (n = 164)

	Hazard ratio	95% CI	P1
Age	1.036	0.982-1.093	0.194
Sex	0.851	0.301-2.403	0.761
Size	1.023	0.974-1.074	0.357
Resection method (en bloc vs piecemeal)	0.680	0.188-2.452	0.555
Histology			0.004
MGD vs LGD	2.837	0.358-22.499	0.324
HGD vs LGD	2.009	0.206-19.630	0.549
CIS vs LGD	186.651	8.813-3953.020	0.001
Site (distal colon vs right and transverse colon)	5.933	1.345-26.175	0.019

¹Cox univariate analysis. LGD: Low-grade dysplasia; MGD: Moderate-grade dysplasia; HGD: High-grade dysplasia; CIS: Carcinoma-in-situ.