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©2010 Baishideng Publishing Group Co.
World J Gastroenterol. Nov 7, 2010; 16(41): 5203-5210
Published online Nov 7, 2010. doi: 10.3748/wjg.v16.i41.5203
Published online Nov 7, 2010. doi: 10.3748/wjg.v16.i41.5203
Table 1 Characteristics of patients enrolled in this study
Patients | 118 |
Gender | |
Female | 44 |
Male | 74 |
Age (yr), median (range) | 49.8 (19-67) |
H. pylori infection (mCGS, mean ± SD) | |
Positive | 41 |
+ | 15 (1.11 ± 0.53) |
++ | 15 (1.68 ± 0.51) |
+++ | 11 (2.42 ± 0.45) |
Negative | 77 (0.61 ± 0.39) |
Indication for CLE | |
Upper GI symptoms | 87 |
Screened for gastric cancer | 31 |
Endoscopic diagnosis | |
Normal stomach | 6 |
Gastritis | 92 |
Peptic ulcer | 5 |
Polyps | 13 |
Early gastric cancer | 2 |
Table 2 Sensitivity, specificity, positive predictive values and negative predictive values of confocal laser endomicroscopy for the diagnosis of normal mucosa, Helicobacter pylori-associated active inflammation, glandular atrophy and intestinal metaplasia (per specimen) [% (95% CI)]
CLE classification | Sensitivity | Specificity | PPV | NPV |
Normal mucosa | 94.6 (91.9-97.4) | 97.4 (95.8-99.1) | 96.5 (94.2-98.7) | 96.1 (94.1-98.1) |
Active inflammation | 98.5 (97.2-99.8) | 94.6 (91.9-97.4) | 95.9 (93.7-97.9) | 98.0 (96.3-99.7) |
Glandular atrophy | 92.9 (87.0-98.9) | 95.2 (93.3-97.0) | 72.5 (63.4-81.7) | 98.9 (98.1-99.9) |
Intestinal metaplasia | 98.6 (95.7-100.0) | 100 (100.0-100.0) | 100 (100.0-100.0) | 99.8 (99.4-100.0) |
Table 3 Confocal laser endomicroscopy and white-light endoscopy in predicting histological changes
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Citation: Wang P, Ji R, Yu T, Zuo XL, Zhou CJ, Li CQ, Li Z, Li YQ. Classification of histological severity of
Helicobacter pylori -associated gastritis by confocal laser endomicroscopy. World J Gastroenterol 2010; 16(41): 5203-5210 - URL: https://www.wjgnet.com/1007-9327/full/v16/i41/5203.htm
- DOI: https://dx.doi.org/10.3748/wjg.v16.i41.5203