Brief Article
Copyright ©2010 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 14, 2010; 16(34): 4329-4334
Published online Sep 14, 2010. doi: 10.3748/wjg.v16.i34.4329
Table 1 Baseline characteristics of the study population (mean ± SD) n (%)
Total patients (n = 284)
Gender (M:F)102:182
Age (yr)52.1 ± 12.2
Hyperechogenic pancreas positive110 (38.7)
Current cigarette smoking70 (24.6)
Current alcohol drinking106 (37.3)
Hypertension (≥ 140/90 mmHg)61 (21.5)
BMI (kg/m2)   23.1 ± 2.9
Fatty liver94 (33.1)
Diabetes mellitus46 (16.2)
Hypercholesterolemia46 (16.1)
CT measurement (n = 132)
SAT area (cm2)  145.6 ± 49.3
VAT area (cm2)   71.7 ± 43.6
Table 2 Comparison between the patients with and without hyperechogenic pancreas (mean ± SD) n (%)
HP negative (n = 174)HP positive (n = 110)P value
Age (yr)48.9 ± 12.057.2 ± 10.7< 0.001
Male gender69 (39.9)33 (30.0)0.099
BMI (kg/m2)22.4 ± 2.824.0 ± 2.7< 0.001
Smoking47 (27.0)23 (20.9)0.245
Alcohol71 (40.8)35 (31.8)0.127
Type 2 DM7 (4.0)12 (10.9)0.024
Hypertension25 (14.4)36 (32.7)< 0.001
Hypercholesterolemia20 (11.5)26 (23.6)0.007
Fatty liver46 (26.4)48 (43.6)0.003
Table 3 Multivariate analysis of the clinical risk factors for hyperechogenic pancreas
P valueOR95% CI
Male gender0.0132.6361.224-5.678
Age older than 60 yr0.0012.8741.537-5.372
Obesity (BMI > 25 kg/m2)0.4391.2960.673-2.496
Smoking0.6121.2270.557-2.701
Alcohol0.4350.7730.405-1.475
Type 2 DM0.6461.3040.420-4.055
Hypertension0.0442.0371.018-4.072
Hypercholesterolemia0.0991.8210.893-3.713
Fatty liver0.0082.2191.226-4.016
Table 4 Comparison of adipose tissue between patients with and without hyperechogenic pancreas n (%)
HP negative (n = 79)HP positive (n = 53)P value
VAT area (cm2)< 0.001
Quartile I (< 35.2)23 (29.1)9 (17.0)
Quartile II (35.2-65.9)25 (31.6)8 (15.1)
Quartile III (65.9-94.0)19 (24.1)14 (26.4)
Quartile IV (> 94.0)12 (15.2)22 (41.5)
SAT area (cm2)0.008
Quartile I (< 109.3)24 (30.4)9 (17.0)
Quartile II (109.3-139.7)22 (27.8)11 (20.8)
Quartile III (139.7-179.2)18 (22.8)16 (30.2)
Quartile IV (> 179.2)15 (19.0)17 (32.1)
Table 5 Multivariable analysis: Unadjusted and adjusted analyses for the relationships of the abdominal adipose tissue area with hyperechogenic pancreas, OR (95% CI)
Unadjusted analysisP valueAdjusted analysis1P value
VAT area (cm2)0.0150.010
Quartile I (< 35.2)ReferenceReference
Quartile II (35.2-65.9)0.646 (0.202-2.059)0.671 (0.214-2.365)
Quartile III (65.9-94.0)1.311 (0.637-6.094)1.997 (0.561-7.107)
Quartile IV (> 94.0)3.491(1.154-10.557)5.665 (1.515-21.180)
SAT area (cm2)0.4140.960
Quartile I (< 109.3 )ReferenceReference
Quartile II (109.3-139.7)1.139 (0.374-3.471)1.016 (0.316-3.271)
Quartile III (139.7-179.2)1.97 (0.637-6.094)1.353 (0.378-4.841)
Quartile IV (> 179.2)2.288 (0.720-7.268)1.227 (0.301-4.992)