Primary site resection is superior for incurable metastatic colorectal cancer

Table 1 Patient characteristics n (%)

Parameter	Total	Primary resection	Palliative surgery
Total cohort	99	38 (100)	36 (100)
Age (median, range)	61.5	61 (50-79)	61 (31-83)
Sex
M	39	20 (53)	19 (53)
F	36	19 (50)	17 (47)
Comorbidity1
0	57	28 (74)	29 (81)
1	12	8 (21)	4 (11)
2	5	2 (5)	3 (8)
3	1	1 (3)	0 (0)
Primary site
Cecum	3	2 (5)	1 (3)
Ascending colon	12	8 (21)	4 (11)
Transverse colon	6	2 (5)	4 (11)
Descending colon	6	5 (13)	1 (3)
Sigmoid colon	12	5 (13)	7 (19)
Rectum	35	16 (42)	19 (53)
Stage2
T
1	0	0 (0)	0 (0)
2	16	10 (26)	6 (17)
3	29	20 (53)	9 (25)
4	29	8 (21)	21 (58)
N
0	18	8 (21)	10 (28)
1	31	19 (50)	12 (33)
2	35	11 (29)	14 (39)
H3
0	31	11 (29)	20 (56)
1	10	5 (13)	5 (14)
2	7	5 (13)	2 (6)
3	26	17 (45)	9 (25)
Lung metastasis
Yes	23	12 (32)	11 (31)
No	51	26 (68)	25 (69)
Peritoneal metastasis
Yes	22	10 (26)	12 (33)
No	52	28 (74)	24 (67)

¹Comorbidity defined using the Charlson index;

²Obtained from the UICC classification;

³The extent of liver involvement is defined: H1: Liver involvement less than 25%; H2: From 25% to 50%; H3: More than 50%.

Table 2 Surgical procedure performed

Group	Procedure	n
Primary resection	Resection with anastomosis	27
	Resection with anastomosis + stoma	3
	Resection without anastomosis	8
Palliative operation	Creation of stoma	27
	Stoma + bypass	3
	Bypass	6

Table 3 Postoperative complications

Postoperative morbidity	Primary resection	Palliative surgery
Wound infection	6	5
Prolonged ileus	4	1
Intraabdominal/pelvic infection	1	2
Urinary tract infection	3	0
Anastomotic leak	2	0
Pneumonia	0	1
Catheter infection	1	0
Gastric hemorrhage	1	0
Liver failure	0	1
Perforation of cancer	0	1
Bleeding from cancer	0	1
Operational death	0	1
Total	18	13
Hospitalization (d) (P = 0.05)	22.7 ± 12.9	18.1 ± 7.9