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©2010 Baishideng.
World J Gastroenterol. Jul 14, 2010; 16(26): 3279-3286
Published online Jul 14, 2010. doi: 10.3748/wjg.v16.i26.3279
Published online Jul 14, 2010. doi: 10.3748/wjg.v16.i26.3279
Table 1 Demographic data about the patients included in this study
Characteristic | ADM (n = 45) | ERAF (n = 45) | P value |
Gender (male/female) | 24/21 | 25/20 | NS |
Age (SD, range) | 18-59 (44.8) | 17-61 (45.1) | NS |
Smoking history, n (%) | 14 (31) | 11 (24) | NS |
Course of disease (SD, range, mo) | 3.0-7.1 (4.6) | 2.8-6.9 (5.1) | NS |
Type of fistula (intrasphincteric/transsphincteric) | 19/26 | 17/28 | NS |
Median follow-up time | 5.7 (5.1-6.4) | 6.1 (5.9-6.5) | NS |
Table 2 Vaizey score system
Never | Rare | Sometimes | Each week | Everyday | |
Frequency of incontinence | 0 | 1 | 2 | 3 | 4 |
Solid | 0 | 1 | 2 | 3 | 4 |
Liquid | 0 | 1 | 2 | 3 | 4 |
Gas | 0 | 1 | 2 | 3 | 4 |
Alteration in lifestyle | No | Yes | |||
Need to wear a pad or plug | 0 | 2 | |||
Use of constipating medication | 0 | 2 | |||
Lack of ability to defer defecation for 15 min | 0 | 4 |
Table 3 Life quality scale system[16]
Physical |
P1 It is difficult for me to get out and do things like going to a movie or to church |
P2 I avoid travelling |
P3 Whenever I am away from home, I try and stay near a toilet as much as possible |
P4 I can’t hold on to my bowel motion long enough to get to the bathroom |
P5 I try to prevent bowel accidents by staying very near a bathroom |
P6 I cut down on how much I eat before I go out |
P7 Whenever I go somewhere new, I make sure I know where the toilets are |
Social |
S1 I avoid visiting my friends |
S2 I avoid staying the night away from home |
S3 It is important to plan my daily activities around my bowel habit |
S4 I leak stool without even noticing it |
S5 I can’t do many things I want to do |
S6 I have sex less often than I would like |
S7 I feel different from other people |
S8 I avoid travelling by plane or public transport |
S9 I avoid going out to eat |
S10 I am afraid to have sex |
Emotional |
E1 I am afraid to go out |
E2 I worry about not being able to get to the toilet in time |
E3 I feel unhealthy |
E4 I feel ashamed |
E5 I worry about bowel accidents |
E6 I feel depressed |
E7 I worry about the smell |
E8 I enjoy life less |
E9 The possibility of bowel accidents is always on my mind |
E10 During the past month have you felt so sad, discouraged, hopeless, or had so many |
Problems that you wondered whether anything was worthwhile? |
Overall sense of well-being |
In general, would you say your health is excellent/very good/good/fair/poor? |
Table 4 Recurrence, fecal incontinence, anal deformity, postoperative pain time, and healing time of patients with ADM or ERAF n (%)
ADM | ERAF | P value | |
n | 45 | 45 | |
Recurrence | 2 (4.45) | 13 (28.89) | 0.0047 |
Fecal incontinence | 1 (2.22) | 4 (8.89) | 0.3574 |
Anal deformity | 0 (0) | 3 (6.67) | 0.2402 |
Postoperative pain time (d) | 1.5 ± 0.5 | 7.5 ± 1.8 | 0.0000 |
Healing time (d) | 7.5 ± 3.5 | 24.5 ± 5.5 | 0.0000 |
Table 5 Recurrence, fecal incontinence, anal deformity, postoperative pain time, and healing time of patients with intrasphincteric fistula, ADM or ERAF n (%)
Intra ADM | Intra ERAF | P value | |
n | 19 | 17 | |
Recurrence | 0 (0.00) | 3 (17.65) | 0.1907 |
Fecal incontinence | 0 (0.00) | 0 (0.00) | |
Anal deformity | 0 (0.00) | 0 (0.00) | |
Postoperative pain time (d) | 1.2 ± 0.4 | 5.5 ± 1.9 | 0.0000 |
Healing time (d) | 7.1 ± 3.4 | 24.6 ± 5.4 | 0.0000 |
Table 6 Recurrence, fecal incontinence, anal deformity, postoperative pain time, and healing time of patients with transsphincteric fistula, ADM or ERAF n (%)
Trans ADM | Trans ERAF | P value | |
n | 26 | 28 | |
Recurrence | 2 (7.69) | 10 (35.71) | 0.0318 |
Fecal incontinence | 1 (3.85) | 4 (14.29) | 0.9390 |
Anal deformity | 0 (0.00) | 3 (10.71) | 0.2615 |
Postoperative pain time (d) | 1.5 ± 0.6 | 8.6 ± 1.4 | 0.0000 |
Healing time (d) | 7.6 ± 3.6 | 25.9 ± 5.7 | 0.0000 |
Table 7 Life quality score in different groups
Table 8 Publications on anal fistula plug in the World
Author | Publication form | Total patients (n) | Crohn’s patients (n) | Follow-up median (mo) | Success rate (%) |
Adamina et al[29], 2010 | Article | 12 | 0 | 12.6 (10-14) | 50.0 |
Schwandner et al[30], 2009 | Article | 60 | 0 | 12 | 62.0 |
Schwandner et al[31], 2009 | Article | 36 | 0 | 9 | 75.0 |
Zubaidi et al[32], 2009 | Article | 23 | 0 | 12 | 83.0 |
Ortiz et al[33], 2009 | Article | 15 | 0 | 12 | 20.0 |
Chung W et al[34], 2009 | Article | 65 | 0 | 12 | 59.3 |
Wang et al[35], 2009 | Article | 29 | 0 | 18 (9.1-26.8) | 34.0 |
Christoforidis et al[36], 2009 | Article | 37 | 4 | 14 (6-22) | 32.0 |
Safar et al[37], 2009 | Article | 35 | 4 | 4 | 14.0 |
Christoforidis et al[38], 2008 | Article | 49 | 4 | 6.5 | 43.0 |
Song et al[39], 2008 | Article | 30 | 0 | 6.3 | 100.0 |
Ky et al[40], 2008 | Article | 45 | 14 | 6.5 (3-13) | 84.0 |
Lawes et al[41], 2008 | Article | 20 | 0 | 7.4 | 24.0 |
Ellis[42], 2007 | Article | 17 | 5 | 6 | 88.0 |
van Koperen et al[43], 2007 | Article | 17 | 1 | 7 | 41.0 |
Ky et al[44], 2007 | Abstract | 37 | 8 | 3 | 84.0 |
Abbas et al[45], 2007 | Abstract | 17 | 0 | 7.4 | 24.0 |
Bohe et al[46], 2007 | Abstract | 32 | 7 | 6 | 65.0 |
Lenisa et al[47], 2007 | Abstract | 27 | 0 | 11 | 63.0 |
Thekkinkattil et al[48], 2007 | Abstract | 40 | 0 | 6 | 40.0 |
Poirier et al[49], 2006 | Abstract | 27 | 0 | 5 | 59.0 |
Champagne et al[50], 2006 | Article | 46 | 0 | 12 | 83.0 |
- Citation: A ba-bai-ke-re MMTJ, Wen H, Huang HG, Chu H, Lu M, Chang ZS, Ai EHT, Fan K. Randomized controlled trial of minimally invasive surgery using acellular dermal matrix for complex anorectal fistula. World J Gastroenterol 2010; 16(26): 3279-3286
- URL: https://www.wjgnet.com/1007-9327/full/v16/i26/3279.htm
- DOI: https://dx.doi.org/10.3748/wjg.v16.i26.3279