Post-gastrectomy spleen enlargement and esophageal varices: Distal vs total gastrectomy

Table 1 Characteristics of patients n (%), (mean ± SD)

	DG group (n = 64)	TG group (n = 28)	P-value
Age (yr)	68.3 ± 10.1	69.3 ± 6.7	0.6522
Sex ratio (male:female)	46:18	20:8	0.9651
Stage
IA	15 (23.4)	5 (17.9)	0.5504
IB	13 (20.3)	7 (25)	0.6160
II	16 (25.0)	7 (25)	1.00
IIIA	17 (26.6)	7 (25)	0.8752
IIIB	3 (4.7)	2 (7.1)	0.6382
Initial disease
Hypertension	10 (15.6)	3 (10.7)	0.7474
Diabetes mellitus	9 (14.1)	3 (10.7)	0.7502
Atrial fibrillation	2 (3.1)	1 (3.6)	1.00
Apoplexy	2 (3.1)	0 (0)	0.5184
Parkinson disease	1 (1.6)	0 (0)	0.3043
Old pulmonary tuberculosis	4 (6.3)	1 (3.6)	1.00
Preoperative platelet count (× 104/μL)	24.8 ± 4.1	24.5 ± 3.4	0.7386
Preoperative spleen diameter (mm)	90.8 ± 8.5	91.9 ± 10.4	0.5908
Preoperative Platelet count/spleen diameter ratio	2744 ± 473	2674 ± 369	0.4921

DG: Distal gastrectomy; TG: Total gastrectomy.

Table 2 Clinical data 3 mo postoperatively n (%), (mean ± SD)

	DG group (n = 64)	TG group (n = 28)	P-value
Platelet count (× 104/μL)	25.8 ± 4.2	25.1 ± 3.9	0.4580
Spleen diameter (mm)	93.9 ± 7.6	96.8 ± 9.5	0.1251
Platelet count/spleen diameter ratio	2769 ± 453	2593 ± 328	0.0674
Esophageal varices
Grade 1	0 (0)	0 (0)	1.00
Grade 2	0 (0)	0 (0)	1.00
Grade 3	0 (0)	0 (0)	1.00
Total occurrence rate	0 (0)	0 (0)	1.00

Grade 1: The varices could be depressed by the endoscope; Grade 2: The varices could not be depressed by the endoscope; Grade 3: The varices were confluent around the esophagus.

Table 3 Clinical data 6 mo postoperatively n (%), (mean ± SD)

	DG group (n = 64)	TG group (n = 28)	P-value
Platelet count (× 104/μL)	26.7 ± 4.3	26.5 ± 3.9	0.8016
Spleen diameter (mm)	95.6 ± 7.6	100.6 ± 9.4	0.0078
Platelet count/spleen diameter ratio	2853 ± 458	2632 ± 373	0.0274
Esophageal varices
Grade 1	0 (0)	0 (0)	1.00
Grade 2	0 (0)	0 (0)	1.00
Grade 3	0 (0)	0 (0)	1.00
Total occurrence rate	0 (0)	0 (0)	1.00

Table 4 Clinical data 12 mo postoperatively n (%), (mean ± SD)

	DG group (n = 64)	TG group (n = 28)	P-value
Platelet count (× 104/μL)	26.8 ± 3.9	27.5 ± 3.7	0.4358
Spleen diameter (mm)	102.4 ± 8.7	105.9 ± 9.0	0.0843
Platelet count/spleen diameter ratio	2628 ± 409	2604 ± 360	0.7887
Esophageal varices
Grade 1	2 (3)	1 (3.6)	1.00
Grade 2	0 (0)	0 (0)	1.00
Grade 3	0 (0)	0 (0)	1.00
Total occurrence rate	2 (3)	1 (3.6)	1.00

Table 5 Clinical data 24 mo postoperatively n (%), (mean ± SD)

	DG group (n = 64)	TG group (n = 28)	P-value
Platelet count (× 104/μL)	26.4 ± 3.7	25.8 ± 4.0	0.4533
Spleen diameter (mm)	104.4 ± 9.8	109.9 ± 10.1	0.0164
Platelet count/spleen diameter ratio	2546 ± 380	2357 ± 365	0.00287
Esophageal varices
Grade 1	2 (3)	2 (7.1)	0.5825
Grade 2	0 (0)	1 (3.6)	0.3043
Grade 3	0 (0)	0 (0)	1.00
Total occurrence rate	2 (3)	3 (10.7)	0.1629

Table 6 Clinical data 36 mo postoperatively n (%), (mean ± SD)

	DG group (n = 64)	TG group (n = 28)	P-value
Platelet count (× 104/μL)	26.3 ± 3.8	25.5 ± 4.3	0.3904
Spleen diameter (mm)	105.6 ± 9.8	110.6 ± 9.6	0.0147
Platelet count/spleen diameter ratio	2515 ± 386	2317 ± 381	0.0256
Esophageal varices
Grade 1	3 (4.7)	3 (10.7)	0.3638
Grade 2	1 (1.6)	1 (3.6)	0.5184
Grade 3	0 (0)	0 (0)	1.00
Total occurrence rate	4 (6.3)	4 (14.3)	0.2082