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©2010 Baishideng.
World J Gastroenterol. Apr 14, 2010; 16(14): 1765-1771
Published online Apr 14, 2010. doi: 10.3748/wjg.v16.i14.1765
Published online Apr 14, 2010. doi: 10.3748/wjg.v16.i14.1765
Table 1 Clinical characteristics of patients
Characteristic | n (%) |
Total | 90 (100.0) |
Gender (M/F) | 59 (65.6)/31 (34.4) |
Median age (yr) | 48 (range: 16-71) |
Underlying disease | |
Multiple myeloma | 46 (51.1) |
Hodgkin’s lymphoma | 23 (25.6) |
Non-Hodgkin’s lymphoma | 15 (4.4) |
Acute myeloblastic leukemia | 4 (4.4) |
Acute lymphoblastic leukemia | 1 (1.1) |
Primitive neuroectodermal tumor | 1 (1.1) |
Conditioning regimen | |
Melphalan | 47 (52.2) |
BEAM | 35 (38.9) |
Busulfex-Cy | 4 (4.4) |
Busulfex-Melphalan | 1 (1.1) |
TBI-Cy-Thiotepa | 1 (1.1) |
Thiotepa-Cy-Bu | 1 (1.1) |
Z-BEAM | 1 (1.1) |
Table 2 Pretransplant HBV serologic results and HBV-related events after transplantation n (%)
Pretransplantation HBV serologic result | HBV-related events after transplantation | |||||
HBsAg | Anti-HBs | Anti-HBc | Anti-HBe | Patients | HBV reactivation/total patients | Loss of antibody/total patients |
Negative | Negative | Negative | Negative | 45 (50.0) | 1/45 | 1/45 |
Negative | Positive | Negative | Negative | 15 (16.7) | - | 8/15 |
Negative | Negative | Positive | Negative | 3 (3.3) | 2/3 | 1/3 |
Negative | Negative | Negative | Positive | 1 (1.1) | - | - |
Positive | Negative | Negative | Negative | 3 (3.3) | - | - |
Positive | Negative | Positive | Positive | 3 (3.3) | - | - |
Negative | Negative | Positive | Positive | 5 (5.6) | - | - |
Negative | Positive | Negative | Positive | 3 (3.3) | - | - |
Negative | Positive | Positive | Negative | 6 (6.7) | - | 4/6 |
Negative | Positive | Positive | Positive | 6 (6.7) | - | - |
Table 3 Characteristics and serologic marker details of the patients with loss of antibody
Patients No. | Age (yr) | Gender | Antibody disappearance time (post-transplantation months) | Time of antibody reappearance (mo) | Disease | |
Anti-HBs | Anti-HBc | |||||
#1 | 71 | F | +6 | - | +18 | MM |
#6 | 59 | F | +6 | - | - | MM |
#8 | 50 | M | +12 | - | +18 | MM |
#10 | 48 | F | +9 | - | - | MM |
#12 | 52 | F | +24 | +6 | - | MM |
#27 | 46 | F | +1 | - | +12 | MM |
#28 | 59 | M | +1 | - | +8 | MM |
#39 | 59 | M | +1 | - | - | MM |
#40 | 30 | M | - | +1 | +6 | NHL |
#41 | 68 | M | - | +3 | - | MM |
#43 | 16 | F | +1 | - | - | PNET |
#48 | 56 | F | +1 | +1 | +6 (anti-HBc) | MM |
#55 | 64 | M | +6 | - | - | MM |
#89 | 23 | F | +3 | - | - | HD |
- Citation: Çeneli &, Özkurt ZN, Acar K, Rota S, Akı ŞZ, Yeğin ZA, Yağcı M, Özenirler S, Sucak GT. Hepatitis B-related events in autologous hematopoietic stem cell transplantation recipients. World J Gastroenterol 2010; 16(14): 1765-1771
- URL: https://www.wjgnet.com/1007-9327/full/v16/i14/1765.htm
- DOI: https://dx.doi.org/10.3748/wjg.v16.i14.1765