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©2010 Baishideng.
World J Gastroenterol. Apr 14, 2010; 16(14): 1727-1734
Published online Apr 14, 2010. doi: 10.3748/wjg.v16.i14.1727
Published online Apr 14, 2010. doi: 10.3748/wjg.v16.i14.1727
Table 1 Clinicopathological features of evaluated colorectal lesions
m/sm-s | sm-d | |
Lesions (n = 112) | 69 | 43 |
Gender (male/female) | 42/27 | 24/19 |
Age (range, yr) | 63.2 (37-79) | 62.5 (32-80) |
Location | ||
Right colon | 29 | 15 |
Left colon | 18 | 12 |
Rectum | 22 | 16 |
Morphology1 | ||
Ip/Is/Isp | 21 | 18 |
IIa/IIa + IIc/IIc | 10 | 16 |
LST-G | 20 | 5 |
LST-NG | 18 | 4 |
Mean size (range, mm) | 32.3 (10-100) | 24.4 (10-90) |
Table 2 Microvascular architecture & invasion depth
Variables | Univariate analysis P-value1 | Multivariate analysis | ||||
P-value1 | Odds ratio | 95% CI | ||||
Non-dense/dense | ||||||
Vessel density | m/sm-s | 1/68 | < 0.001 | 0.001 | 402.5 | 12.4-13 133.1 |
sm-d | 33/10 | |||||
Negative/positive | ||||||
Vessel regularity | m/sm-s | 8/61 | < 0.001 | 0.038 | 15.9 | 1.2-219.1 |
sm-d | 38/5 | |||||
Negative/positive | ||||||
Caliber regularity | m/sm-s | 44/25 | < 0.001 | 0.056 | 17.3 | 0.9-323.4 |
sm-d | 42/1 | |||||
Short/long | ||||||
Vessel length | m/sm-s | 20/49 | < 0.001 | 0.161 | 0.2 | 0.01-2.10 |
sm-d | 37/6 | |||||
Positive/negative | ||||||
Meandering | m/sm-s | 49/20 | 0.002 | 0.110 | 0.1 | 0.01-1.60 |
sm-d | 41/2 | |||||
Wide/narrow | ||||||
Caliber | m/sm-s | 62/7 | NS | |||
sm-d | 41/2 |
Table 3 Assessment of the carcinomatous invasion depth based on microvascular architecture
Microvascular architecture | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | Accuracy (%) |
Vessel density | 33/43 | 68/69 | 0.97 (0.85-0.99) | 0.87 (0.78-0.94) | 90.2 |
Non-dense | 0.77 (0.61-0.88) | 0.99 (0.92-0.99) | |||
Vessel regularity | 38/43 | 61/69 | 0.83 (0.69-0.92) | 0.92 (0.83-0.97) | 88.4 |
Negative | 0.88 (0.75-0.96) | 0.88 (0.78-0.95) | |||
Caliber regularity | 42/43 | 25/69 | 0.49 (0.38-0.60) | 0.96 (0.80-0.99) | 59.8 |
Negative | 0.98 (0.88-0.99) | 0.36 (0.25-0.49) | |||
Vessel length | 37/43 | 49/69 | 0.65 (0.51-0.77) | 0.89 (0.78-0.96) | 76.8 |
Short | 0.86 (0.84-0.99) | 0.71 (0.59-0.81) | |||
Meandering | 41/43 | 20/69 | 0.46 (0.35-0.56) | 0.91 (0.71-0.99) | 54.5 |
Positive | 0.95 (0.84-0.99) | 0.29 (0.19-0.41) | |||
Caliber | 41/43 | 7/69 | 0.40 (0.30-0.50) | 0.78 (0.40-0.97) | 42.9 |
Wide | 0.95 (0.84-0.99) | 0.10 (0.04-0.20) |
Table 4 Assessment of the carcinomatous invasion depth: comparison between microvascular architecture & pit pattern analysis
Microvascular architecture | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | Accuracy (%) |
Non-dense vessel density and/or negative vessel regularity | 38/43 | 60/69 | 0.81 (0.67-0.91) | 0.92 (0.83-0.97) | 87.5 |
0.88 (0.75-0.96) | 0.87 (0.77-0.94) | ||||
Non-dense vessel density and negative vessel regularity | 35/43 | 69/69 | 1.00 (0.90-1.00) | 0.90 (0.81-0.95) | 92.9 |
0.81 (0.67-0.92) | 1.00 (0.95-1.00) | ||||
Pit pattern (Invasive pattern) | 37/43 | 68/69 | 0.97 (0.86-0.99) | 0.92 (0.83-0.97) | 93.8 |
0.86 (0.72-0.95) | 0.99 (0.92-0.99) |
- Citation: Fukuzawa M, Saito Y, Matsuda T, Uraoka T, Itoi T, Moriyasu F. Effectiveness of narrow-band imaging magnification for invasion depth in early colorectal cancer. World J Gastroenterol 2010; 16(14): 1727-1734
- URL: https://www.wjgnet.com/1007-9327/full/v16/i14/1727.htm
- DOI: https://dx.doi.org/10.3748/wjg.v16.i14.1727