Review
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Feb 21, 2009; 15(7): 788-803
Published online Feb 21, 2009. doi: 10.3748/wjg.15.788
Table 1 Epidemiology and gene markers of IBD[264849]
EpidemiologyGene markers of IBD
Incidence per 1000000.5-2.0 (China); 2-14 (North America)
Prevalence per 1000001-23 (China); 26-246 (North America)
GeographyNorthern Countries > Southern Countries; Lower (China)
Age of onset (yr)20-35 (China)
SexM > F (China)
RaceWhites > Blacks; Lower (Chinese)
Possible genetic associations (Chinese)TNF-308A, CARD15 (NOD2), MIF-173, NAT2, NKG2D, STAT6, CTLA-4, MICA-MICB, HLA-DRB1, HLA class II, IL-18, IL-4, MICA-A5, CD14, TLR4, Fas-670, p53, NF-κB; Chromosome 3, 5, 7, 12, 16 ,19