Complete response to radiation therapy of orbital metastasis from hepatocellular carcinoma

Table 1 Critical structures mean dose for original and boost IMRT plans

Structure	Original mean dose (Gy) (2 Gy/fx)	Boost mean dose (Gy) (1.8 Gy/fx)	Total dose (Gy)
Chiasm	6.98	3.55	10.52
Left eye	15.93	1.42	17.34
Left optic nerve	13.3	1.96	15.26
Right eye	30.7	3.96	34.65
Right optic nerve	34.09	6.46	40.55

IMRT: Intensity modulated radiation therapy; Gy: Gray.

Table 2 Case reports of orbital metastases from hepatocellular carcinoma

Author	Gender	Age (yr)	Treatment	Survival
Gupta et al[10]	M	45	None	NA
Loo et al[8]	F	71	Transcranial orbitotomy	3 mo
Schwab et al[12]	M	19	Anterior orbitotomy with biopsy	2 wk (moribund state)
Wakisaka et al[9]	M	58	Left frontotemporal craniotomy	11 mo
Lubin et al[22]	M	69	3000 cGy in 2 wk	NA
Zubler et al[5]	M	64	4000 cGy over 8 wk + chemotherapy	3 mo
Srinivasan et al[4]	F	76	None	NA
Scolyer et al[23]	M	77	None	NA
Font et al[13]	F	79	Palliative RT	3 yr
Kim et al[6]	F	56	None	2 mo
Machado-Netto et al[11]	M	57	Megestrol acetate and Gemcitabine	15 mo
Hirunwiwatkul et al[7]	F	74	NA	2 mo
Tranfa et al[14]	M	85	Anterior orbitotomy with excisional biopsy	NA
Phanthumchinda et al[15]	F	29	5400 cGy in 4 wk	NA

NA: Not available; RT: Radiation therapy; F: Female; M: Male.