Brief Article
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Nov 21, 2009; 15(43): 5481-5488
Published online Nov 21, 2009. doi: 10.3748/wjg.15.5481
Table 1 Clinical characteristics of patients with extrahepatic metastases of hepatocellular carcinoma
Characteristicsn (%)
Age (yr)55.8 ± 14.4
Male:Female108:32
Hepatitis B virus surface antigen66 (47)
Hepatitis C virus antibody30 (21.4)
Previous hepatic resection
Yes66 (47)
Single hepatic resection57
Multiple hepatic resection7
Liver transplantation2
No74 (53)
Location of metastatic tumor
Lung25 (17.8)
Bone47 (33.6)
Brain28 (20)
Soft tissue35 (25)
Heart2 (1.4)
Table 2 Clinical characteristics of patients who underwent surgical resection of extrahepatic metastases of hepatocellular carcinoma
Characteristicsn (%)
Age (yr)54.1 ± 14.9
Male:Female64:22
Hepatitis B virus surface antigen46 (53)
Hepatitis C virus antibody22 (21.4)
Concurrent treated intrahepatic lesion
Yes59 (69)
No27 (31)
Location of metastatic tumor
Lung11 (12.8)
Bone24 (27.9)
Brain25 (29.1)
Soft tissue24 (27.9)
Heart2 (2.3)
Table 3 Clinical features of patients who underwent surgical resection for extrahepatic metastases from HCC with favorable outcomes
No. ofpatientAge (yr)/SexTreatments for intrahepatic HCCExtrahepatic metastases
Follow-up after metastases (mo)Outcome
Duration to metastases (mo)Location/Management
144/MaleHepatic resection: 1 time7Lung/wedge resection40Alive
TACE: 1 time
236/FemaleHepatic resection: 1 time16T-spine/resection of tumor89Dead
TACE: 1 timeLung/wedge resection
331/FemaleHepatic resection: 1 time11Transverse colon and peritoneal soft tissue/surgical resection67Alive
TACE: 3 times
451/MaleHepatic resection: 1 time32Peritoneal soft tissue/surgical resection96Alive
TACE: 2 times
PEI: 1 time
RFA:1 time
567/MaleTACE: 11 times7Abdominal wall/wide excision57Dead
PEI: 8 times