Lack of correlation between p53 codon 72 polymorphism and anal cancer risk

Table 1 Demographic characteristics of cancer patients and controls n (%)

Characteristics	Cases	Controls	P
Gender
Male	7 (22)	22 (21)	NS
Female	25 (78)	81 (79)
Race
White	28 (87)	96 (93)	NS
Non-white	4 (13)	7 (7)
Age (yr); mean (range)	60.3 (30-81)	47.7 (40-72)	< 0.001
Total	32 (100)	103 (100)

NS: Not significant.

Table 2 Distribution of p53 codon 72 polymorphism in cancer patients and controls n (%)

	Total	Arg/Arg	Arg/Pro	Pro/Pro	OR1	CI	P
Anal cancer	32	10 (31.2)	19 (59.4)	3 (9.4)	1.6	0.6-4.9	0.325
Controls	103	31 (30.1)	62 (60.2)	10 (9.7)

¹Adjusted for age. Arg/Arg vs Arg/Pro and Pro/Pro.