Original Articles
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Sep 28, 2009; 15(36): 4511-4517
Published online Sep 28, 2009. doi: 10.3748/wjg.15.4511
Table 1 Characteristics of patients with advanced biliary tract cancer
Patients (n = 124)n (%)
Age (yr)
Range32.8-84.8
Median64.8
mean ± SD63.4 ± 11.0
Male:female61:63 (49:51)
Gallbladder cancer33 (26.6)
Mass forming type47 (37.9)
Intraductal growth type44 (35.5)
Histological type
Well differentiated8 (6.5)
Moderately differentiated80 (64.5)
Poorly differentiated36 (29)
Stage1
 I9 (7.3)
II20 (16.1)
III31 (25)
IV64 (51.6)
Chemotherapy62 (50)
Partial response9 (14.5)
Stable disease27 (43.5)
Progressive disease26 (42)
Table 2 EGFR and HER2 expression and clinicopathological factors (Cox’s model)
ParameterEGFR 2+ and 3+ tumorsPHER2 2+ and 3+ tumorsP
Gallbladder cancer5/138/34
Mass forming type6/240.0887/470.517
Intraductal growth type11/1910/43
Histological type
Well differentiated2/31/8
Moderately differentiated16/390.51120/800.202
Poorly differentiated4/144/36
Stage1
 I3/44/9
II2/60.3174/200.059
III8/179/31
IV9/298/64
Chemotherapy
Partial response2/34/9
Stable disease3/130.2964/270.156
Progressive disease5/135/26