Effect of early preoperative 5-fluorouracil on the integrity of colonic anastomoses in rats

Table 1 Leukocyte, platelet and haemoglobin values of blood samples in each group (mean ± SE)

Groups	Leukocytes (109/L)		Platelets (109/L)		Haemoglobin (g/dL)
	3rd d	7th d	3rd d	7th d	3rd d	7th d
Control	9.0 ± 3.04	7.6 ± 3.4	1117 ± 169	1270 ± 229	11 ± 1.7	12.6 ± 1.2
IP	9.1 ± 3.3	9.7 ± 2.4	808 ± 203	1228 ± 194	10.5 ± 1.7	11.9 ± 0.45
IV	7.4 ± 4.7	15.9 ± 5.2	736 ± 243	1542 ± 289	9.6 ± 1.13	11.16 ± 1.9

Table 2 Histological scores of anastomotic colon healing in all groups on the 3rd and 7th postoperative days (mean ± SE)

Groups	3rd d			7th d
	Control	IP	IV	Control	IP	IV
Granulation	1.66 ± 0.70	2.14 ± 0.89	1.42 ± 0.53	2.66 ± 0.50	2.71 ± 0.48	2.57 ± 0.53
Re-epithelization	1.55 ± 1.66	2.71 ± 2.21	1.00 ± 0.00	4.77 ± 1.20	5.28 ± 0.95	2.42 ± 2.14
Muscular tissue	1.00 ± 0.00	1.00 ± 0.00	1.00 ± 0.00	1.22 ± 0.44	1.42 ± 0.44	1.14 ± 0.37