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©2009 The WJG Press and Baishideng.
World J Gastroenterol. Aug 28, 2009; 15(32): 3999-4004
Published online Aug 28, 2009. doi: 10.3748/wjg.15.3999
Published online Aug 28, 2009. doi: 10.3748/wjg.15.3999
Table 1 Characteristics of patients in the diclofenac and control groups1
Diclofenac group (n = 40) | Control group (n = 40) | P | |
Variables | |||
Age (yr)2 | 60.3 ± 16.1 | 59.3 ± 14.5 | 0.766 |
Female sex | 15 (37.5) | 22 (55.0) | 0.116 |
Bile duct canulation time (min)3 | 5.0 (3.0-5.0) | 5.0 (3.0-10.0) | 0.601 |
Operation time (min)3 | 15 (15-20) | 15 (10-25) | 0.904 |
Sphincterotomy | |||
Precut | 10 (25) | 12 (30) | 0.617 |
Pancreatic duct injection | 19 (47.5) | 18 (45.0) | 0.823 |
Pancreatic duct cannulation, twice or more | 8 (20.5) | 6 (15.0) | 0.556 |
Post-ERCP pancreatitis | 3 (7.5) | 7 (17.5) | 0.176 |
Final diagnosis | |||
BD stone | 23 (57.5) | 11 (27.5) | |
SOD | 3 (7.5) | 10 (25.0) | 0.082 |
Biliopancreatic tumors | 5 (12.5) | 9 (22.5) | |
Others4 | 9 (22.5) | 10 (25.0) |
Table 2 Incidence of post-ERCP pacreatitis in different subgroups1
Diclofenac group (n = 40) | Control group (n = 40) | P | |
Variables | |||
Age group (yr) | |||
> 60 | 2/23 | 4/20 | 0.300 |
≤ 60 | 1/17 | 3/20 | 0.420 |
Sex | |||
Male | 0/25 | 2/18 | 0.850 |
Female | 3/15 | 5/22 | 0.092 |
Pre-cut sphincterotomy | |||
Yes | 1/10 | 4/12 | 0.210 |
No | 2/30 | 3/28 | 0.590 |
Pancreatic duct injection | |||
Yes | 2/19 | 4/18 | 0.350 |
No | 1/21 | 3/22 | 0.330 |
Pancreatic duct cannulation, twice or more | 2/8 | 1/6 | 0.730 |
SOD | |||
Yes | 2/3 | 2/10 | 0.150 |
No | 1/37 | 5/30 | 0.0471 |
Table 3 Serum amylase level (mean ± SE, IU/L) following ERCP in diclofenac and control groups
Group | Amylase 4 h | Amylase 8 h | Amylase 24 h |
Diclofenac | 223.95 ± 33.45 | 218.39 ± 35.44 | 161.82 ± 31.03 |
Control | 283.15 ± 82.74 | 308.34 ± 96 | 231.56 ± 57.73 |
- Citation: Senol A, Saritas U, Demirkan H. Efficacy of intramuscular diclofenac and fluid replacement in prevention of post-ERCP pancreatitis. World J Gastroenterol 2009; 15(32): 3999-4004
- URL: https://www.wjgnet.com/1007-9327/full/v15/i32/3999.htm
- DOI: https://dx.doi.org/10.3748/wjg.15.3999