Soluble intercellular adhesion molecule-1, D-lactate and diamine oxidase in patients with inflammatory bowel disease

doi:10.3748/wjg.15.3916

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Aug 21, 2009 (publication date) through May 3, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 21, 2009; 15(31): 3916-3919
Published online Aug 21, 2009. doi: 10.3748/wjg.15.3916

Table 1 Comparison of the values of WBC, serum sICAM-1, DAO and plasma D-lactate between the test IBD group and control group (mean ± SD)

Group	n	WBC (×10⁹/L)	sICAM-1 (ng/mL)	DAO (U/mL)	D-lactate (μg/mL)
Test	69	7.24 ± 2.33	206.57 ± 79.21^a	9.91 ± 5.64^a	1.46 ± 0.94^a
Control	30	4.82 ± 1.46	107.25 ± 52.41	2.04 ± 0.95	0.82 ± 0.47

^aP < 0.01 vs control group. sICAM-1: Soluble intercellular adhesion molecule-1; DAO: Diamine oxidase; WBC: White blood cells; IBD: Inflammatory bowel disease.

Table 2 Comparison of the values of the 4 substances in the ulcerative colitis (UC) group and Crohn’s disease (CD) group (mean ± SD)

Group	n	WBC (×10⁹/L)	sICAM-1 (ng/mL)	DAO (U/mL)	D-lactate (μg/mL)
UC	49	7.40 ± 2.61	212.94 ± 69.89^a	8.65 ± 3.54^a	6.35 ± 2.35^a
CD	20	7.29 ± 2.25	208.31 ± 51.05^b	8.58 ± 2.49^b	6.32 ± 2.23^b
Control	30	4.82 ± 1.46	107.25 ± 52.41	2.04 ± 1.35	0.82 ± 0.17

^aP < 0.01 vs control group,

^bP < 0.01 vs control group.

Table 3 Comparison of WBC, sICAM-1, DAO and D-lactate of the IBD group before and after treatment (mean ± SD)

IBD	WBC (×10⁹/L)	sICAM-1 (ng/mL)	DAO (U/mL)	D-lactate (μg/mL)
Pre-treatment	7.24 ± 2.33	206.57 ± 79.21	9.91 ± 5.64	1.46 ± 0.94
Post-treatment	5.21 ± 3.21	146.21 ± 64.43^a	6.42 ± 2.18^a	0.52 ± 0.32^a

^aP < 0.01 vs pre-treatment.

Citation: Song WB, Lv YH, Zhang ZS, Li YN, Xiao LP, Yu XP, Wang YY, Ji HL, Ma L. Soluble intercellular adhesion molecule-1, D-lactate and diamine oxidase in patients with inflammatory bowel disease. World J Gastroenterol 2009; 15(31): 3916-3919
URL: https://www.wjgnet.com/1007-9327/full/v15/i31/3916.htm
DOI: https://dx.doi.org/10.3748/wjg.15.3916